Abstract
Background: Airway obstruction occurs due to an increase in airway resistance, so the determination of Raw must be considered for the evaluation of its presence and severity classification especially in individuals with difficultty to perform forced maneuvres.
Aims: To determine the presence of airway obstruction according to FEV1/FVC<70%, Raw≥0.240KPa/l/s and Raw≥0.380KPa/l/s criteria; Estimate the sensitivity and specificity of the Raw≥0.240KPa/l/s and Raw≥0.380KPa/l/s criteria; Classify the severity degree of airway obstruction according to FEV1 and Raw.
Methods: Cross-sectional study. The sample included 579 individuals who performed spirometry and whole body plethysmography during 2019. For the detection of airway obstruction, the criteria mentioned above were considered. In the presence of airway obstruction defined by FEV1/FVC ratio, its severity was established according to FEV1% and when defined by Raw≥0.240KPa/l/s was based on Raw severity degrees.
Results: The Raw≥0.240KPa/l/s detected the presence of airway obstruction in 61.8% of individuals, the FEV1/FVC<70% in 55.1% and Raw≥0.380KPa/l/s in 29.5%. The Raw≥0.240KPa/l/s showed a sensitivity of 79.9% and a specificity of 47.6% and the Raw≥0.380KPa/l/s of 59.2% e 92.7%, respectively. Relatively to airway obstruction severity, through FEV1 analysis, 35.1% were mild, 18.5% moderate, 15.7% moderatly severe, 20.4% severe and 10.3% very severe. Through the Raw KPa/l/s analysis, 62.9% were mild, 26.5% moderate and 10.6% severe.
Conclusion: Raw showed a high capacity to identify airway obstruction and allowed to classify the obstruction severity, which should be valued in the study of individuals with suspected obstructive disease with difficulty of perform the spirometry
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3837.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021