Late Breaking Abstract - The mortality predicting factors at admission and during hospitalisation of pateints with SARS COV2

Abstract

Methods: These is a retrospective case control study conducted in patients admitted at University Hospital Shefqet Ndroqi Tirana/Albania during November-December 2020 with diagnosis of bilateral pneumonia due to infection with SARS COV2 virus.100 patients who died in hospital from SARS-COV2 related complications were compared with 100 patient with SARS-COV2 recovered from hospital. Laboratory and radiological data were compared at admission and the end of hospital treatment in both groups.

Results: Patients older than 67 years are 3.3 times(t) more likely to die compared to patients younger than 67(p=0.00).Chest CT involvement >65% are 2.4(t) more likely to die compared to patients with <65%(p=0.00). In the first period of time analysis: Patients with ferritin levels >780ng/ml are 3.06(t) more likely to die compared to patients with ferritin <780ng/ml(p=0.00).D-dimer >790 ng/ml are 2.5(t) more likely to die than D-dimer <790 ng/ml(p=0.00).Patients with blood urea nitrogen levels >40.5 mg/dl are 3.3(t) more likely to die than Nitrogen <40.5 mg/dl(p=0.00).Neutrophiles/lymphocytes ratio level >10 are 2.80(t) more likely to die than ratio <10(p=0.00). In the analysis before leaving the hospital or death:PCR levels >78.5 mg/l are 5.9(t) more likely to die compared with <78.5 mg/l(p=0.00). Neutrophiles/lymphocytes ratio >17.8 are 24.3(t) more likely to die compared with ratio <17.8(p=0.00).D-dimer level >1835 ng/ml are 22.7(t) more likely to die compared to <1835ng/ml(p=0.000).Ferritin >1331ng/ml are 3(t) more likely to die compared to <1331ng/ml(p=0.01)

Conclusion: The increase in PCR, D-dimer, Ferritin, BUN, Neutrophiles/Lymphocytes values is a bad prognostic factor in SARS-COV2 hospitalized patient