Abstract
The interpretation of ferritin in COVID-19 pneumonia patients (pts) is still a challenge for the clinician.
The aim was to estimate the diagnostic and prognostic role of ferriitin on admission in hospitalized patients with confirmed COVID-19 pneumonia.
Materials and methods: We observed 53 pts (age–59(52;65), men – 22(41,5%)) hospitalized with COVID-19 pneumonia, divided into 3 groups (G): G1 – 36 pts with moderate COVID-19 pneumonia, G2 – 12 pts with severe, G3 – 5 pts with critical COVID-19. Ferritin level was performed at admission before treatment, statistical analysis.
Results: At admission the level of ferritin was increased in 44 (83,0%) of pts, the highest levels had patients with critical course where it exceeds the upper diagnostical maximum rather in all patients. Individual analysis showed that 31 patients from G1 and 5 patients from G2 had progression of COVID-19 pneumonia in dynamic. ROC-analysis showed that ferritin more than 190 ng/ml is associated with progression of disease (Fig.1). Odds Ratio analysis shows the powerful reliable connection between increased level of ferritin at this level at admission and disease progression (OR=168; CI=95% (9.16; 3080.0); p<0.001).
Conclusion: increase of the level of ferritin more than 190 ng/ml at admission of COVID-19 pneumonia pts is associated with critical course of disease and increases the risk of progression rather in 168 times.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3656.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021