Abstract
Introduction: MDN is a multisystem disease that affects the brain, nerves and muscles including those of the respiratory system with progressive weakness1 (Rafiq, MK et al. Practical Neurology 2012;12:166-176). 20 to 40% of patients end up requiring feeding via a long-term gastrostomy. Approximately 1/3 also have restrictive lung disease with respiratory failure invariably requiring NIV.
Objective: We try to answer whether there are any parameters that can predict the need for NIV during PEG-tube insertion.
Methods: Electronic records of 172 patients undergoing PEG insertion at the university hospitals of North Midlands between 2016 and 2019 were analyzed. Statistical analyses was conducted using SPSS.
Results: 157 patients had a diagnosis of MDN. 93 were men and 79 were women with a mean age of 67.6. 92.7% had PEG insertion while 6.7% had RIG. A total of 105 patients required NIV cover during PEG insertion. Of the cohort that was known to require long-term NIV, 89.4% required NIV cover while only half of those MND patients not on long-term NIV required it. 67.9% of patients with PaCO2 less than 6 and 87% of those with a PaCO2 of 6 or more needed NIV support as shown in figure 1.
Conclusion: MDN patients already established on NIV, those with a PaCO2 of more than 6 and those with a PaO2 lower than 10 were more likely to require NIV cover during PEG insertion.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3582.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021