Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • ERS Guidelines
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • Peer reviewer login
  • Alerts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • ERS Guidelines
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • Peer reviewer login
  • Alerts
  • Subscriptions

Airway oscillometry after single lung transplantation is characterised by abnormal respiratory reactance

Joan P.Y. Sim Sim, David R. Darley, Kristopher Nilsen, Riva Shirol, Brigitte M. Borg, Jaideep Vazirani, Bronwyn Levvey, Gregory Snell, Marshall Plit, Katrina O. Tonga
European Respiratory Journal 2021 58: PA3497; DOI: 10.1183/13993003.congress-2021.PA3497
Joan P.Y. Sim Sim
1Lung Transplant & Thoracic Medicine Unit, St Vincent’s Hospital, Sydney Australia; St Vincent’s Clinical School, The University of New South Wales, Sydney Australia, Sydney, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: joansim99@gmail.com
David R. Darley
1Lung Transplant & Thoracic Medicine Unit, St Vincent’s Hospital, Sydney Australia; St Vincent’s Clinical School, The University of New South Wales, Sydney Australia, Sydney, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kristopher Nilsen
2Lung Transplant & Physiology Services, Respiratory Medicine, The Alfred Hospital, Melbourne Australia, Melbourne, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Riva Shirol
3Lung Transplant & Physiology Services, Respiratory Medicine, The Alfred Hospital, Sydney Australia, Sydney, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Brigitte M. Borg
2Lung Transplant & Physiology Services, Respiratory Medicine, The Alfred Hospital, Melbourne Australia, Melbourne, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jaideep Vazirani
2Lung Transplant & Physiology Services, Respiratory Medicine, The Alfred Hospital, Melbourne Australia, Melbourne, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bronwyn Levvey
2Lung Transplant & Physiology Services, Respiratory Medicine, The Alfred Hospital, Melbourne Australia, Melbourne, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gregory Snell
2Lung Transplant & Physiology Services, Respiratory Medicine, The Alfred Hospital, Melbourne Australia, Melbourne, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marshall Plit
1Lung Transplant & Thoracic Medicine Unit, St Vincent’s Hospital, Sydney Australia; St Vincent’s Clinical School, The University of New South Wales, Sydney Australia, Sydney, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Katrina O. Tonga
4Lung Transplant & Thoracic Medicine Unit, St Vincent’s Hospital, Sydney Australia; St Vincent’s Clinical School, The University of New South Wales, Sydney Australia; Woolcock Institute and Faculty of Medicine & Health, The University of Sydney, Sydney Australia, Sydney, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
Loading

Abstract

Aim: Single (SLTx) and double lung transplantation (DLTx) are therapeutic options for end-stage interstitial lung disease (ILD). The aim of this study is to describe oscillometry indices in stable SLTx compared to DLTx recipients.

Methods: Oscillometry & spirometry were performed on all stable LTx recipients at 2 Australian centres from 2020-2021 using TremoFlo C-100 to obtain resistance (R5, R5-19), reactance (X5) and reactance area (Ax). Subjects with baseline, acute or chronic lung allograft dysfunction were excluded. SLTx for ILD (SLTx-ILD) recipients were compared with DLTx for ILD (DLTx-ILD) and were matched by age and gender.

Results: 17 SLTx-ILD were included and compared with 10 matched stable DLTx-ILD. Baseline demographics of SLTx-ILD [88% males; mean age 64 (SD 5)] and DLTx-ILD [90% males; mean age 63 (SD 6)] were similar. Median X5 (-1.86 vs -1.14, p=0.02) and Ax (12.60 vs 5.57, p=0.04) differed significantly between SLTx-ILD and DLTx-ILD recipients, but resistance (R5, R5-19) measurements did not.

Conclusion: SLTx for ILD is characterised by significantly worse X5 and Ax (increased elastance) as compared to DLTx for ILD. The abnormal reactance, in addition to insignificant differences in resistance measurements between SLTx and DLTx, may be due to the fibrotic contralateral native lung. However, contribution from other factors such as differences in lung size matching needs to be assessed. Longitudinal oscillometry studies are required to ascertain whether abnormal reactance – when assessed against patients' baseline measurements – can be indicative of earlier progressive lung graft dysfunction and a worse prognosis in SLTx, as compared to using traditional methods.

  • Idiopathic pulmonary fibrosis
  • Experimental approaches

Footnotes

Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3497.

This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2021
Previous
Back to top
Vol 58 Issue suppl 65 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Airway oscillometry after single lung transplantation is characterised by abnormal respiratory reactance
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Airway oscillometry after single lung transplantation is characterised by abnormal respiratory reactance
Joan P.Y. Sim Sim, David R. Darley, Kristopher Nilsen, Riva Shirol, Brigitte M. Borg, Jaideep Vazirani, Bronwyn Levvey, Gregory Snell, Marshall Plit, Katrina O. Tonga
European Respiratory Journal Sep 2021, 58 (suppl 65) PA3497; DOI: 10.1183/13993003.congress-2021.PA3497

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Airway oscillometry after single lung transplantation is characterised by abnormal respiratory reactance
Joan P.Y. Sim Sim, David R. Darley, Kristopher Nilsen, Riva Shirol, Brigitte M. Borg, Jaideep Vazirani, Bronwyn Levvey, Gregory Snell, Marshall Plit, Katrina O. Tonga
European Respiratory Journal Sep 2021, 58 (suppl 65) PA3497; DOI: 10.1183/13993003.congress-2021.PA3497
Reddit logo Technorati logo Twitter logo Connotea logo Facebook logo Mendeley logo

Jump To

  • Article
  • Info & Metrics
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Short and mid-term outcomes of lung transplant recipients with COVID-19
  • Late Breaking Abstract - Prognostic impact of decreased erector spinae muscle radiographic density after lung transplantation
  • Covid 19 in a lung transplant population
Show more Transplantation

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2023 by the European Respiratory Society