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Automatic lung sound analysis accuracy: a validation study

Olga Kharevich, Elena Lapteva, Irina Kovalenko, Elena Katibnikova, Anastasia Pozdnyakova, Anatoliy Laptev, Valentin Korovkin, Irina Bezruchko, Galina Novskaya, Irina Lantuchova, Ekaterina Monosova, Maria Zhurovich, Ivan Dulub, Olga Adamovich, Viktoria Hotko, Alexander G. Mathioudakis, Helena Binetskaya, Aleksey Karankevich, Vitali Dubinetski
European Respiratory Journal 2021 58: PA3456; DOI: 10.1183/13993003.congress-2021.PA3456
Olga Kharevich
1Belarusian State Medical Academy of Postgraduate Education, Department of Pulmonology and Tuberculosis, Minsk, Belarus
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  • For correspondence: Olkash1@yandex.ru
Elena Lapteva
1Belarusian State Medical Academy of Postgraduate Education, Department of Pulmonology and Tuberculosis, Minsk, Belarus
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Irina Kovalenko
1Belarusian State Medical Academy of Postgraduate Education, Department of Pulmonology and Tuberculosis, Minsk, Belarus
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Elena Katibnikova
1Belarusian State Medical Academy of Postgraduate Education, Department of Pulmonology and Tuberculosis, Minsk, Belarus
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Anastasia Pozdnyakova
1Belarusian State Medical Academy of Postgraduate Education, Department of Pulmonology and Tuberculosis, Minsk, Belarus
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Anatoliy Laptev
1Belarusian State Medical Academy of Postgraduate Education, Department of Pulmonology and Tuberculosis, Minsk, Belarus
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Valentin Korovkin
1Belarusian State Medical Academy of Postgraduate Education, Department of Pulmonology and Tuberculosis, Minsk, Belarus
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Irina Bezruchko
2Minsk Regional Pediatric Clinical Hospital, Pediatric Department, Minsk, Belarus
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Galina Novskaya
3Republican Scientific and Practical Centre of Pulmonology and Tuberculosis, Pulmonology Department, Minsk, Belarus
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Irina Lantuchova
3Republican Scientific and Practical Centre of Pulmonology and Tuberculosis, Pulmonology Department, Minsk, Belarus
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Ekaterina Monosova
44th City Clinical Hospital named after N.E. Savchenko, Pulmonology Department, Minsk, Belarus
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Maria Zhurovich
56th City Clinical Hospital, Pulmonology Department, Minsk, Belarus
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Ivan Dulub
56th City Clinical Hospital, Pulmonology Department, Minsk, Belarus
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Olga Adamovich
6City Children's Infectious Diseases Clinical Hospital, Pediatric Department, Minsk, Belarus
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Viktoria Hotko
75th City Clinical Hospital, Minsk, Pulmonology Department, Minsk, Belarus
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Alexander G. Mathioudakis
8The University of Manchester, Clinical Research Fellow & Honorary Lecturer in Respiratory Medicine, Manchester, United Kingdom
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Helena Binetskaya
9Healthy Networks OÜ, Tallin, Estonia
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Aleksey Karankevich
9Healthy Networks OÜ, Tallin, Estonia
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Vitali Dubinetski
9Healthy Networks OÜ, Tallin, Estonia
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Abstract

Background: LungPass is an Automatic Lung Sound Analysis app-enabled device, including an electronic wireless stethoscope and a mobile application developed using neural networks training methodology. Such stethoscope could have crucial practical applications, such as the early identification of acute and exacerbations of chronic airway diseases. LungPass has achieved high accuracy in the identification of the main lung sounds in a training cohort. We present the accuracy characteristics of LungPass, evaluated in an independent, validation cohort.

AccuracySpecificitySensitivityPositive predictive valueNegative predictive value
Normal breathing89.1%91.3%82.5%75.9%94.0%
Crackles84.1%85.4%80.0%64.7%92.8%
Wheezes95.6%99.2%85.0%97.1%95.2%
Artifacts94.4%99.6%78.8%98.4%93.4%

Methods: The accuracy characteristics of the LungPass were evaluated in a validation cohort of 110 patients with different lung diseases (74 adults and 36 children). Gold standard was defined as the judgement of a panel of expert pulmonologists about the recorded sounds.

Results: Our analysis was based on 320 sound recordings, including 80 sounds that were judged to be artifacts, in advance. The overall accuracy of the device in classifying lung sounds, in comparison with the gold standard was 81.6% [95% CI: 73.1%-90.1%]. The accuracy characteristics LungPass for identifying specific lung sounds are summarized in table 1. The auscultation was safe. Three patients developed hyperventilation but no other local or systemic adverse events were observed.

Conclusion: The LungPass platform is accurate. In the future, it could be used to complement clinical examination, or for patients’ telemonitoring.

  • Primary care
  • Telemedicine
  • Monitoring

Footnotes

Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3456.

This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2021
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Automatic lung sound analysis accuracy: a validation study
Olga Kharevich, Elena Lapteva, Irina Kovalenko, Elena Katibnikova, Anastasia Pozdnyakova, Anatoliy Laptev, Valentin Korovkin, Irina Bezruchko, Galina Novskaya, Irina Lantuchova, Ekaterina Monosova, Maria Zhurovich, Ivan Dulub, Olga Adamovich, Viktoria Hotko, Alexander G. Mathioudakis, Helena Binetskaya, Aleksey Karankevich, Vitali Dubinetski
European Respiratory Journal Sep 2021, 58 (suppl 65) PA3456; DOI: 10.1183/13993003.congress-2021.PA3456

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Automatic lung sound analysis accuracy: a validation study
Olga Kharevich, Elena Lapteva, Irina Kovalenko, Elena Katibnikova, Anastasia Pozdnyakova, Anatoliy Laptev, Valentin Korovkin, Irina Bezruchko, Galina Novskaya, Irina Lantuchova, Ekaterina Monosova, Maria Zhurovich, Ivan Dulub, Olga Adamovich, Viktoria Hotko, Alexander G. Mathioudakis, Helena Binetskaya, Aleksey Karankevich, Vitali Dubinetski
European Respiratory Journal Sep 2021, 58 (suppl 65) PA3456; DOI: 10.1183/13993003.congress-2021.PA3456
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