Abstract
Introduction: The increase in lung volumes is frequently accompanied by air flow limitation in individuals with COPD, and contributes to the mortality and quality of life of these patients.
Aims: Characterization of lung volumes in individuals with COPD according to several criteria of pulmonary hyperinflation; Determine the sensitivity and specificity of the several criteria opposed to a mixed criteria; determine the agreement coefficients between the several criteria considered and the mixed criteria.
Methods: Cross-sectional study. 349 individuals with COPD underwent functional respiratory tests. Mixed criteria was considerate as presence of pulmonary hyperinflation: RV> 140% pred, FRC> 120% pred, TLC> 120% and RV/TLC>35%. The isolated criteria RV> 120% pred, FRC> 120% pred, TLC> 120% pred and RV/TLC> 35% were also analyzed.
Results: The mixed criteria identified the presence of hyperinflation in 24.4% of the sample and the isolated parameters: RV> 120% in 63.9%, FRC> 120% in 58.5%, TLC> 120% in 23.2% and RV/TLC> 35% in 91.1%. Having the mixed criteria as a reference for the presence/absence of pulmonary hyperinflation, the RV criteria> 120% obtained a sensitivity (S) of 98.8% and a specificity (E) of 68.7%, FRC> 120% (S -100% and E-79.1%), TLC> 120% (S-87.2% and 97.2%) and RV/TLC> 35% (S-97.7% and 15.9%). Regarding the agreement coefficient, it was observed for RV> 120% (K = 0.576), FRC> 120% (0.709), TLC> 120% (0.860) and RV/TLC> 35% (0.093).
Conclusion: The TLC> 120% criteria was the one that obtained results that overlap those of the mixed criteria. If using a single criteria to identify the presence of hyperinflation, the authors propose the TLC> 120%.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3439.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021