Abstract
Background: Despite the determination of maximal respiratory pressures (MRP) are not frequently evaluated in COPD, they are essential for the assessment of respiratory muscle dysfunction.
Aims: To characterize the MRP according airway obstruction severity; To determine the odds ratio for radiographic and CT scan features and MRP reduction.
Methods: Cross-sectional study. The sample included 73 COPD patients that performed lung function tests, 65 of those performed chest radiography and 67 CT scan. Airway obstruction was classified as mild, moderate and severe. The radiography criteria were diaphragm rectification, ribs horizontalization, increased of retrosternal space and hyperlucency. Through CT scan were obtained information about anteroposterior space, presence of emphysema-type (centrilobular, panlobular or paraseptal) and distribution (upper, lower or multilobular).
Results: Higher MIP means were observed in mild obstruction compared to severe obstruction and in moderate obstruction compared to severe obstruction (p<0.05). For decreased MIP and MEP significant odds ratio was obtained in the presence of emphysema (2.41;1.38), increased retrosternal space (1.47;1;40), imaging of lung hyperinflation (1.81;1.57) and multilobular emphysema (2.57;1.25). For decreased MEP only were obtained significant odds ratio in the presence of diaphragm rectification (1.31), increased anteroposterior space (1.21) and centrilobular emphysema (1.90).
Conclusions: MRP should be determined in COPD patients that present greater severity of airway obstruction, presence of emphysema, increased retrosternal space, presence of lung hyperinflation and multilobular emphysema, because they are associated with the reduction of MIP and MEP
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3435.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021