Abstract
Introduction: Colorectal cancer is the third human cancer. Its prognosis remains poor due to its late diagnosis, the frequency of local recurrences and the high metastatic potential. The management of lung metastases from colorectal cancers (LMCCR) has evolved considerably.
Methodology: This was a retrospective study of patients operated for LMCCR in the thoracic and cardiovascular surgery department of the Abderrahmen Mami hospital in Ariana, Tunisia.
Results: We collected 29 cases: 17 men and 12 women with a sex ratio of 1.4. The average age was 58.7 years old. The procedure consisted of metastasectomy in 23 patients, lobectomy in five patients, bilobectomy in one patient, pneumonectomy in one patient and exploratory thoracotomy for the remaining two. The postoperative follow-up was straightforward for 24 patients, 82.8%.
The mean survival was 43.76 months. The main prognostic factors were: age, grade of cell differentiation of the primary cancer, histo-prognosis stage and degree of extension of CRC, lymph node status, therapeutic attitude towards colorectal tumors and free interval between the diagnosis of the primary and the detection of lung metastasis. The rate of ACE, the presence of metastases and the surgical attitude were not prognostic criteria.
Conclusion: Surgery has become one of the linchpins of multimodal treatment of LMCCR because its impact on survival has been demonstrated. However, a better knowledge of the prognostic factors would improve treatment.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3408.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021