Abstract
Introduction: Globally, chronic lung diseases are responsible for approximately 4 million premature deaths annually. Spirometry is one of the methods used in the diagnosis and management of chronic lung diseases. The Global Lung Initiative of 2012 managed to develop multi ethnic spirometry equations for use across all age groups. Since their publication, several validation studies have done to establish their suitability with the various ethnicities. To date no study has been done in Zimbabwe to validate the GLI 2012 among adult women. The study aimed to validate the GLI 2012 African -American module in adult Zimbabwean women.
Methods: A total of 566 healthy, non-smoking adult women from urban and peri-urban households in Zimbabwe were recruited over period of 18 months. Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV 1), and the ratio of FEV1 to FVC were measured according to the American Thoracic Society and European Respiratory Society Guidelines.
Results: The findings from the study supports the use of GLI 2012 African -American module in adult Zimbabweans (mean for FVC, FEV1 and ratio is within ±0.5). Also, the analysis of relationships between anthropometry and African-American GLI2012 SRE z-scores showed weak correlations between ±0.14. Weak correlations provide no evidence of bias in the generation of spirometry z-scores in this population.
Conclusion: The African-American GLI2012 SRE predict the lung function capacities in adult Zimbabwean women.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3358.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021
