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Adherence of drug-resistant tuberculosis patients to treatment in Tashkent, 2019-2020

Ruzilya Usmanova, Nargiza Parpieva, Irina Liverko, Hayk Davtyan, Sevak Alaverdyan, Jamshid Gadoev
European Respiratory Journal 2021 58: PA3342; DOI: 10.1183/13993003.congress-2021.PA3342
Ruzilya Usmanova
1Republican Specialized Scientific-Practical Medical Center of Phthisiology and Pulmonology, Tashkent, Uzbekistan
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  • For correspondence: ruzilenka@yandex.ru
Nargiza Parpieva
1Republican Specialized Scientific-Practical Medical Center of Phthisiology and Pulmonology, Tashkent, Uzbekistan
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Irina Liverko
1Republican Specialized Scientific-Practical Medical Center of Phthisiology and Pulmonology, Tashkent, Uzbekistan
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Hayk Davtyan
2Tuberculosis Research and Prevention Center, NGO, Nor Hachn, Armenia
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Sevak Alaverdyan
3Bielefeld University, Bielefeld Graduate School of Economics and Management, Bielefeld, Germany
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Jamshid Gadoev
4World Health Organization country office in Uzbekistan, Tashkent, Uzbekistan
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Abstract

Poor adherence tо drug-resistant tuberculosis (DR-TB) treatment is а well known public health problem worldwide. Exploration of factors associated with low DR-TB treatment adherence is important for improving the care of the patients.

The aim of this study was to assess the adherence of DR-TB patients during the intensive phase of hospital treatment by using the validated eight-item Morisky Medication Adherence Scale (MMAS-8) and to study the socio-demographic and clinical factors associated with treatment adherence. A total of 179 DR-TB patients were included in study. This was an analytical cross-sectional study exploring period of 2019-2020. Data was collected from patients’ histories and using the MMAS-8.

Among 141 patients who were answered questionnaire the high level of DR-TB treatment adherence was observed in 19%, average level was in 40% and low in 41% of patients (Figure).

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The analysis showed that socio-demographic variables like of being older, lack of family, alcohol user were significantly related to average and low adherence. Clinical factors such as relapse DR-TB and cases with focal, disseminated and fibrocavernous types of DR-TB were also associated with average and low DR-TB treatment adherence.

Future research on DR-TB treatment adherence is needed to find potential causes for increasing adherence to DR-TB treatment.

  • Adults
  • MDR-TB (multidrug-resistant tuberculosis)
  • Adherence

Footnotes

Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3342.

This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2021
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Adherence of drug-resistant tuberculosis patients to treatment in Tashkent, 2019-2020
Ruzilya Usmanova, Nargiza Parpieva, Irina Liverko, Hayk Davtyan, Sevak Alaverdyan, Jamshid Gadoev
European Respiratory Journal Sep 2021, 58 (suppl 65) PA3342; DOI: 10.1183/13993003.congress-2021.PA3342

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Adherence of drug-resistant tuberculosis patients to treatment in Tashkent, 2019-2020
Ruzilya Usmanova, Nargiza Parpieva, Irina Liverko, Hayk Davtyan, Sevak Alaverdyan, Jamshid Gadoev
European Respiratory Journal Sep 2021, 58 (suppl 65) PA3342; DOI: 10.1183/13993003.congress-2021.PA3342
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  • Treatment of multidrug-resistant tuberculosis in Uzbekistan from 2012 to 2018: does practice follow policy?
  • The effects of bedaquiline and fluoroquinolone-based treatment regimens in patients with MDR/XDR-TB on QT prolongation
  • MDR-TB- A THREE YEAR RURAL TERTIARY CARE HOSPITAL EXPERIENCE
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