Abstract
Objectives: To identify the main risk factors associated with deaths caused by COVID-19 infection.
Material and methods: We performed a retrospective study that focused on the evolution of all patients confirmed with COVID-19 and hospitalized in our clinic in the first wave of the pandemic, between 30.03-31.05.2020. We colected demographic data, comorbidities, clinical, paraclinical manifestations and survival rate from all patients. The data were analyzed and interpreted by statistical methods (mean values, standard deviations, p / one-way Anova).
Results: There were a total of 254 hospitalized patients, with a mean age of 50.83 ± 26.5 years, mostly female (51.9%). Of these, 225 patients were discharged recovered and 29 patients died. Major differences between these two groups, respectively recovered versus deceased were in terms of age (48.4 years vs 69.6 years), sex (68.9% of the deceased being men), C Protein values (41.07mg/l vs 167.94mg/l) and D-dimers (0.69pg/ml vs 4.93pg/ml). The significant comorbidities associated to deaths were hypertension at 58.6%, diabetes at 34.48%, neurological pathology at 17.24%, obesity at 13.79% and chronic hemodialysis at 6.89%). The mortality rate among male patients was more than double compared to female (16.39% vs 6.81%).
Conclusions: The main risk factors with extremely high statistical significance (p <0.001) identified in patients who died with COVID-19 were age (over 69.6 years), male sex, high values of C protein (over 41.07 mg / l) and the presence of hypertension and diabetes. Other significant risk factors (p<0,05) are also chronic neurological disease, obesity and chronic kidney disease.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3260.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021