Abstract
Introduction: In recent years, cases of detection of slow-growing non-tuberculosis mycobacteria in patients operated on for tuberculosis have become more frequent.
Objective: Revealing the differences between morphological picture of tuberculosis and non-tuberculous mycobacteriosis in the lung resection material of patients with combined pathology.
Methods: A morphological, microbiological and molecular genetic study of the surgical material of 38 patients was carried out. All the patients had a confirmed diagnosis of tuberculosis, and slowly growing non-tuberculosis mycobacterias were found in the surgical material.
Results: The spread of non-tuberculosis mycobacteria in patients with pulmonary tuberculosis is accompanied by abundant lymphoid infiltration of the pulmonary parenchyma, the formation of numerous histiocytic-macrophage granulomas without necrosis, which is especially typical of M. avium (22.5%) and M. intracellulare (7.5%). Lymphoid-histiocytic infiltration of the walls of the terminal bronchioles and peribronchial pulmonary parenchyma, as well as single fibrous necrosis are characteristic for M. Kansasii (30%) and M. Xenopi (27.5%).
Conclusion: The obtained data are necessary for the differential diagnosis of pulmonary tuberculosis and non-tuberculous mycobacteriosis.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3084.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021
