SNOT-22 items and association with objective measures in dupilumab-treated patients with severe chronic rhinosinusitis with nasal polyps from SINUS-24 and SINUS-52 trials
Joaquim Mullol, Giorgio Walter Canonica, Martin Wagenmann, Andre Coste, Peter Hellings, Scott Nash, Siddhesh Kamat, Urvi Mujumdar, Jérôme Msihid, Asif H Khan, Shahid Siddiqui, Juby A Jacob-Nara, Yamo Deniz, Paul Rowe
European Respiratory Journal 2021 58: PA2520; DOI: 10.1183/13993003.congress-2021.PA2520
Joaquim Mullol
1Hospital Clínic, IDIBAPS, Universitat de Barcelona, CIBERES, Barcelona, Catalonia, Spain
Giorgio Walter Canonica
2Asthma & Allergy Clinic, Department of Biomedical Sciences, Humanitas University & IRCCS Humanitas Research Hospital, Milan, Italy
Martin Wagenmann
3Department of Otorhinolaryngology, Düsseldorf University Hospital (UKD), Düsseldorf, Germany
Andre Coste
4Henri Mondor University Hospital of Creteil, Creteil, France
Peter Hellings
5Department of Otorhinolaryngology—Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium
Scott Nash
6Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States of America
Siddhesh Kamat
6Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States of America
Urvi Mujumdar
7Sanofi, Cambridge, MA, United States of America
Jérôme Msihid
8Sanofi, Chilly-Mazarin, France
Asif H Khan
8Sanofi, Chilly-Mazarin, France
Shahid Siddiqui
6Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States of America
Juby A Jacob-Nara
7Sanofi, Cambridge, MA, United States of America
Yamo Deniz
6Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States of America
Paul Rowe
9Sanofi, Bridgewater, NJ, United States of America

Tables
SNOT-22 item improvement (Wk 24) Least squares mean difference vs PBO (Wk 24) Smell/taste
Yes/noNasal blockage
Yes/noNPS –1.78*/–1.19* –1.90*/–1.01* LMK –5.77*/–4.26* –6.22*/–3.28* *P<0.0001 vs PBO
Vol 58 Issue suppl 65
Table of Contents
SNOT-22 items and association with objective measures in dupilumab-treated patients with severe chronic rhinosinusitis with nasal polyps from SINUS-24 and SINUS-52 trials
Joaquim Mullol, Giorgio Walter Canonica, Martin Wagenmann, Andre Coste, Peter Hellings, Scott Nash, Siddhesh Kamat, Urvi Mujumdar, Jérôme Msihid, Asif H Khan, Shahid Siddiqui, Juby A Jacob-Nara, Yamo Deniz, Paul Rowe
European Respiratory Journal Sep 2021, 58 (suppl 65) PA2520; DOI: 10.1183/13993003.congress-2021.PA2520
SNOT-22 items and association with objective measures in dupilumab-treated patients with severe chronic rhinosinusitis with nasal polyps from SINUS-24 and SINUS-52 trials
Joaquim Mullol, Giorgio Walter Canonica, Martin Wagenmann, Andre Coste, Peter Hellings, Scott Nash, Siddhesh Kamat, Urvi Mujumdar, Jérôme Msihid, Asif H Khan, Shahid Siddiqui, Juby A Jacob-Nara, Yamo Deniz, Paul Rowe
European Respiratory Journal Sep 2021, 58 (suppl 65) PA2520; DOI: 10.1183/13993003.congress-2021.PA2520