Abstract
Introduction: Many UK workers have had paid, extended periods away from work due to the COVID-19 pandemic. In those with suspected occupational asthma (OA) this has enabled assessment of serial peak expiratory flow (PEF) over long periods away from their workplace.
Methods: Those who had been followed up by telephone or face-to-face between March and December 2020, had completed serial PEF measurements while at work (pre-March 2020), and then during a long period away from work were included. Workers were asked to complete 4 weeks of readings taking them every 2 hours from waking to sleeping each day, whether in the workplace or not. Data was analysed using the OASYS software program.
Results: 10 patients completed serial PEF measurements during the time periods specified. 7 workers showed an improvement in their mean PEFs with prolonged time away from work. Table 1 shows the results.
Conclusion: Although the diagnosis of OA is usually based on analysis of serial PEFs performed during short, alternating episodes at and away from work, PEFs recorded during longer periods away from the workplace have provided evidence of OA in some patients with equivocal PEF results beforehand and confirmed OA in others.
Exposure | Time since last exposure (months) | Mean PEF at work (off work) | ABC score at work (off work) | Pred PEF |
Cleaning agents | 5 | 400 (449) | -2.13 (-6.94) | 401 |
Cleaning agents | 0.17 | 453 (501) | 20.5 (4.66) | 359 |
Epoxy glues | 4 | 583 (644) | 25.2 (0) | 600 |
Chloramines | 4 | 372 (427) | 6.8 (-11.7) | 348 |
Cleaning agents | 4 | 395 (465) | 35.0 (0) | 322 |
Diesel | 1 | 576 (627) | 30.7 (0) | 523 |
Isocyanates | 8 | 554 (678) | 38.5 (0) | 500 |
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA1905.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021