Abstract
Introduction: Tuberculosis (TB) is one of the global health problems. In the context of COVID-19 pandemic, an increase in TB incidence and mortality is not unlikely.
Aim: To assess impact of COVID-19 on the course of pulmonary TB.
Materials and methods: Evaluation results of 25 patients with pulmonary TB and a history of COVID-19 (m.-52%, f.-48%, age-33.2+14.4 years) were analyzed. PCR results for SARS-CoV-2 RNA were positive in all 25 patients. Clinical forms of pulmonary TB during COVID -19 disease: chronic TB-88%, new TB cases -12%. MDR in 80%. Background diseases included: type 2 diabetes mellitus (12%), cardiovascular diseases (12%), COPD (20%).
Results: The need for hospitalization in the Infectious Diseases Department was reported in 44%. Clinical symptoms of COVID-19: weakness-24%, increased body temperature -16 %; complications included: viral pneumonia with 5% to 75% lung damage (CT 2 - CT 4) – in 28% of observations, respiratory failure of stage 2-3 - 12%, hydrothorax - 8%, hemorrhagic syndrome - 8%. Along with COVID-19 treatment, patients received TBDs. According to the chest CT scan results, at month 2, the progression of TB disease was observed in 52%, at months 2-6 - residual changes in patients with viral pneumonia were reported in 71.4%. At month 9, 16% of patients continued to have complains of dry cough and shortness of breath during exercise, weakness was reported in 28%.
Conclusion: According to the chest CT scan, the following results were reported: 2 months after COVID-19 - progression of TB disease (52%), 2-6 months after COVID-19 - residual changes s after viral pneumonia (71.4%). The persistence of respiratory complaints after 9 months was associated with COVID-19 sequela
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA1020.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021