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Table of Contents

01 June 2021; volume 57, issue 6

Editorials

  • You have accessRestricted access
    Time for precision medicine in systemic sclerosis-associated pulmonary arterial hypertension
    David Launay, Sébastien Sanges, Vincent Sobanski
    European Respiratory Journal 57 (6) 2100205; DOI: 10.1183/13993003.00205-2021 Published 24 June 2021
  • You have accessRestricted access
    Ambulatory management of secondary spontaneous pneumothorax: a mirage, or a solution on the horizon?
    Srinivas R. Mummadi, José M. Porcel
    European Respiratory Journal 57 (6) 2100003; DOI: 10.1183/13993003.00003-2021 Published 24 June 2021
  • You have accessRestricted access
    Methylxanthines in COPD: yes to caffeine, no to theophylline
    Ken M. Kunisaki, Don D. Sin
    European Respiratory Journal 57 (6) 2004564; DOI: 10.1183/13993003.04564-2020 Published 10 June 2021
  • You have accessRestricted access
    The coming-of-age of bedaquiline: a tale with an open ending
    Lorenzo Guglielmetti, Francis Varaine
    European Respiratory Journal 57 (6) 2100066; DOI: 10.1183/13993003.00066-2021 Published 10 June 2021
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    Shifting the paradigm: unilateral infiltrates and ARDS?
    Antoni Torres, Enric Barbeta, Tobias Welte
    European Respiratory Journal 57 (6) 2100043; DOI: 10.1183/13993003.00043-2021 Published 10 June 2021
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    Improving adherence to asthma medications: same-old, same-old?
    Mark Weatherall
    European Respiratory Journal 57 (6) 2004284; DOI: 10.1183/13993003.04284-2020 Published 4 June 2021
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    Evidence of air pollution exposure and new asthma onset: further justification for cleaner air
    George D. Thurston, Alison Lee
    European Respiratory Journal 57 (6) 2100064; DOI: 10.1183/13993003.00064-2021 Published 4 June 2021

ERS Official Documents

  • ERS statement

    • You have accessRestricted access
      ERS statement on chronic thromboembolic pulmonary hypertension
      Marion Delcroix, Adam Torbicki, Deepa Gopalan, Olivier Sitbon, Frederikus A. Klok, Irene Lang, David Jenkins, Nick H. Kim, Marc Humbert, Xavier Jais, Anton Vonk Noordegraaf, Joanna Pepke-Zaba, Philippe Brénot, Peter Dorfmuller, Elie Fadel, Hossein-Ardeschir Ghofrani, Marius M. Hoeper, Pavel Jansa, Michael Madani, Hiromi Matsubara, Takeshi Ogo, Ekkehard Grünig, Andrea D'Armini, Nazzareno Galie, Bernhard Meyer, Patrick Corkery, Gergely Meszaros, Eckhard Mayer, Gérald Simonneau
      European Respiratory Journal 57 (6) 2002828; DOI: 10.1183/13993003.02828-2020 Published 17 June 2021
      • Russian translation

Task Force Report

  • Open Access
    World Health Organization recommendations on the treatment of drug-resistant tuberculosis, 2020 update
    Fuad Mirzayev, Kerri Viney, Nguyen Nhat Linh, Licé Gonzalez-Angulo, Medea Gegia, Ernesto Jaramillo, Matteo Zignol, Tereza Kasaeva
    European Respiratory Journal 57 (6) 2003300; DOI: 10.1183/13993003.03300-2020 Published 4 June 2021

Original Articles

  • Pulmonary vascular disease

    • Open Access
      Identifying early pulmonary arterial hypertension biomarkers in systemic sclerosis: machine learning on proteomics from the DETECT cohort
      Yasmina Bauer, Simon de Bernard, Peter Hickey, Karri Ballard, Jeremy Cruz, Peter Cornelisse, Harbajan Chadha-Boreham, Oliver Distler, Daniel Rosenberg, Martin Doelberg, Sebastien Roux, Oliver Nayler, Allan Lawrie
      European Respiratory Journal 57 (6) 2002591; DOI: 10.1183/13993003.02591-2020 Published 24 June 2021
  • Pleural disease

    • You have accessRestricted access
      Ambulatory management of secondary spontaneous pneumothorax: a randomised controlled trial
      Steven P. Walker, Emma Keenan, Oliver Bintcliffe, Andrew E. Stanton, Mark Roberts, Justin Pepperell, Ian Fairbairn, Edward McKeown, James Goldring, Nadeem Maddekar, James Walters, Alex West, Amrithraj Bhatta, Matthew Knight, Rachel Mercer, Rob Hallifax, Paul White, Robert F. Miller, Najib M. Rahman, Nick A. Maskell
      European Respiratory Journal 57 (6) 2003375; DOI: 10.1183/13993003.03375-2020 Published 24 June 2021
    • Open Access
      Epidemiology of pleural empyema in English hospitals and the impact of influenza
      David T. Arnold, Fergus W. Hamilton, Tim T. Morris, Tim Suri, Anna Morley, Vicky Frost, Ian B. Vipond, Andrew R. Medford, Rupert A. Payne, Peter Muir, Nick A. Maskell
      European Respiratory Journal 57 (6) 2003546; DOI: 10.1183/13993003.03546-2020 Published 17 June 2021
  • COPD

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      The effect of low-dose corticosteroids and theophylline on the risk of acute exacerbations of COPD: the TASCS randomised controlled trial
      Christine R. Jenkins, Fu-Qiang Wen, Allison Martin, Peter J. Barnes, Bartolome Celli, Nan-Shan Zhong, Jin-Ping Zheng, Anish Scaria, Gian-Luca Di Tanna, Thomas Bradbury, Norbert Berend on behalf of the TASCS study investigators
      European Respiratory Journal 57 (6) 2003338; DOI: 10.1183/13993003.03338-2020 Published 10 June 2021
  • Tuberculosis

    • You have accessRestricted access
      Impact of bedaquiline on treatment outcomes of multidrug-resistant tuberculosis in a high-burden country
      Dumitru Chesov, Jan Heyckendorf, Sofia Alexandru, Ana Donica, Elena Chesov, Maja Reimann, Valeriu Crudu, Victor Botnaru, Christoph Lange
      European Respiratory Journal 57 (6) 2002544; DOI: 10.1183/13993003.02544-2020 Published 10 June 2021
  • Critical care

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      Viable virus aerosol propagation by positive airway pressure circuit leak and mitigation with a ventilated patient hood
      Shane A. Landry, Jeremy J. Barr, Martin I. MacDonald, Dinesh Subedi, Darren Mansfield, Garun S. Hamilton, Bradley A. Edwards, Simon A. Joosten
      European Respiratory Journal 57 (6) 2003666; DOI: 10.1183/13993003.03666-2020 Published 24 June 2021
    • You have accessRestricted access
      Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study
      Tài Pham, Antonio Pesenti, Giacomo Bellani, Gordon Rubenfeld, Eddy Fan, Guillermo Bugedo, José Angel Lorente, Antero do Vale Fernandes, Frank Van Haren, Alejandro Bruhn, Fernando Rios, Andres Esteban, Luciano Gattinoni, Anders Larsson, Daniel F. McAuley, Marco Ranieri, B. Taylor Thompson, Hermann Wrigge, Laurent J. Brochard, John G. Laffey on behalf of the LUNG SAFE Investigators and the European Society of Intensive Care Medicine Trials Group
      European Respiratory Journal 57 (6) 2003317; DOI: 10.1183/13993003.03317-2020 Published 10 June 2021
  • Asthma

    • You have accessRestricted access
      The benefits of a systematic assessment of respiratory health in illness-susceptible athletes
      James H. Hull, Anna R. Jackson, Craig Ranson, Freddie Brown, Moses Wootten, Mike Loosemore
      European Respiratory Journal 57 (6) 2003722; DOI: 10.1183/13993003.03722-2020 Published 24 June 2021
    • Open Access
      A randomised controlled trial of the effect of a connected inhaler system on medication adherence in uncontrolled asthmatic patients
      Alison Moore, Andrew Preece, Raj Sharma, Liam G. Heaney, Richard W. Costello, Robert A. Wise, Andrea Ludwig-Sengpiel, Giselle Mosnaim, Jamie Rees, Ryan Tomlinson, Ruth Tal-Singer, David A. Stempel, Neil Barnes
      European Respiratory Journal 57 (6) 2003103; DOI: 10.1183/13993003.03103-2020 Published 4 June 2021
    • You have accessRestricted access
      Long-term exposure to low-level air pollution and incidence of asthma: the ELAPSE project
      Shuo Liu, Jeanette Therming Jørgensen, Petter Ljungman, Göran Pershagen, Tom Bellander, Karin Leander, Patrik K.E. Magnusson, Debora Rizzuto, Ulla A. Hvidtfeldt, Ole Raaschou-Nielsen, Kathrin Wolf, Barbara Hoffmann, Bert Brunekreef, Maciej Strak, Jie Chen, Amar Mehta, Richard W. Atkinson, Mariska Bauwelinck, Raphaëlle Varraso, Marie-Christine Boutron-Ruault, Jørgen Brandt, Giulia Cesaroni, Francesco Forastiere, Daniela Fecht, John Gulliver, Ole Hertel, Kees de Hoogh, Nicole A.H. Janssen, Klea Katsouyanni, Matthias Ketzel, Jochem O. Klompmaker, Gabriele Nagel, Bente Oftedal, Annette Peters, Anne Tjønneland, Sophia P. Rodopoulou, Evangelia Samoli, Doris Tove Kristoffersen, Torben Sigsgaard, Massimo Stafoggia, Danielle Vienneau, Gudrun Weinmayr, Gerard Hoek, Zorana Jovanovic Andersen
      European Respiratory Journal 57 (6) 2003099; DOI: 10.1183/13993003.030992020 Published 4 June 2021
  • Cough

    • You have accessRestricted access
      Prevalence, progression and impact of chronic cough on employment in Northern Europe
      Henrik Johansson, Ane Johannessen, Mathias Holm, Bertil Forsberg, Vivi Schlünssen, Rain Jõgi, Michael Clausen, Eva Lindberg, Andrei Malinovschi, Össur Ingi Emilsson
      European Respiratory Journal 57 (6) 2003344; DOI: 10.1183/13993003.03344-2020 Published 4 June 2021
  • Rare lung diseases

    • You have accessRestricted access
      Machine learning can predict disease manifestations and outcomes in lymphangioleiomyomatosis
      Saisakul Chernbumroong, Janice Johnson, Nishant Gupta, Suzanne Miller, Francis X. McCormack, Jonathan M. Garibaldi, Simon R. Johnson
      European Respiratory Journal 57 (6) 2003036; DOI: 10.1183/13993003.03036-2020 Published 4 June 2021
  • Imaging

    • You have accessRestricted access
      Functional respiratory imaging provides novel insights into the long-term respiratory sequelae of bronchopulmonary dysplasia
      Kristien Vanhaverbeke, Monique Slaats, Mohammed Al-Nejar, Niek Everaars, Annemiek Snoeckx, Maarten Spinhoven, Haroun El Addouli, Eline Lauwers, Annelies Van Eyck, Benedicte Y. De Winter, Kim Van Hoorenbeeck, Jozef De Dooy, Ludo Mahieu, Benjamin Mignot, Jan De Backer, Antonius Mulder, Stijn Verhulst
      European Respiratory Journal 57 (6) 2002110; DOI: 10.1183/13993003.02110-2020 Published 4 June 2021
  • Cystic fibrosis

    • Open Access
      Rescue of multiple class II CFTR mutations by elexacaftor+tezacaftor+ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator
      Onofrio Laselva, Claire Bartlett, Tarini N.A. Gunawardena, Hong Ouyang, Paul D.W. Eckford, Theo J. Moraes, Christine E. Bear, Tanja Gonska
      European Respiratory Journal 57 (6) 2002774; DOI: 10.1183/13993003.02774-2020 Published 17 June 2021
  • Cystic fibrosis and basic science

    • You have accessRestricted access
      IL-17A from innate and adaptive lymphocytes contributes to inflammation and damage in cystic fibrosis lung disease
      Matthias Hagner, Melanie Albrecht, Matteo Guerra, Peter Braubach, Olga Halle, Zhe Zhou-Suckow, Simone Butz, Danny Jonigk, Gesine Hansen, Carsten Schultz, Anna-Maria Dittrich, Marcus A. Mall
      European Respiratory Journal 57 (6) 1900716; DOI: 10.1183/13993003.00716-2019 Published 4 June 2021
  • Infection and basic science

    • Open Access
      TNF-mediated alveolar macrophage necroptosis drives disease pathogenesis during respiratory syncytial virus infection
      Leonardo Duarte Santos, Krist Helen Antunes, Stéfanie Primon Muraro, Gabriela Fabiano de Souza, Amanda Gonzalez da Silva, Jaqueline de Souza Felipe, Larissa Cardoso Zanetti, Rafael Sanguinetti Czepielewski, Karen Magnus, Marcelo Scotta, Rita Mattiello, Fabio Maito, Ana Paula Duarte de Souza, Ricardo Weinlich, Marco Aurélio Ramirez Vinolo, Bárbara Nery Porto
      European Respiratory Journal 57 (6) 2003764; DOI: 10.1183/13993003.03764-2020 Published 17 June 2021

Reviews

  • You have accessRestricted access
    Epigenetics and pulmonary diseases in the horizon of precision medicine: a review
    Giuditta Benincasa, Dawn L. DeMeo, Kimberly Glass, Edwin K. Silverman, Claudio Napoli
    European Respiratory Journal 57 (6) 2003406; DOI: 10.1183/13993003.03406-2020 Published 10 June 2021
  • You have accessRestricted access
    Targeting cystic fibrosis inflammation in the age of CFTR modulators: focus on macrophages
    Jonathan L. Gillan, Donald J. Davidson, Robert D. Gray
    European Respiratory Journal 57 (6) 2003502; DOI: 10.1183/13993003.03502-2020 Published 4 June 2021

Agora

  • Research letters

    • You have accessRestricted access
      A case series on the use of steroids and mycophenolate mofetil in idiopathic and heritable pulmonary veno-occlusive disease: is there a role for immunosuppression?
      Carmel Bergbaum, Chinthaka B. Samaranayake, Alex Pitcher, Emma Weingart, Thomas Semple, Maria Kokosi, Athol U. Wells, David Montani, Konstantinos Dimopoulos, Colm McCabe, Aleksander Kempny, Carl Harries, Elizabeth Orchard, S. John Wort, Laura C. Price
      European Respiratory Journal 57 (6) 2004354; DOI: 10.1183/13993003.04354-2020 Published 24 June 2021
    • Open Access
      The high mental health burden of “Long COVID” and its association with on-going physical and respiratory symptoms in all adults discharged from hospital
      Sindhu B. Naidu, Amar J. Shah, Anita Saigal, Colette Smith, Simon E. Brill, James Goldring, John R. Hurst, Hannah Jarvis, Marc Lipman, Swapna Mandal
      European Respiratory Journal 57 (6) 2004364; DOI: 10.1183/13993003.04364-2020 Published 24 June 2021
    • Open Access
      Screening for tuberculosis among high-risk groups attending London emergency departments: a prospective observational study
      Rishi K. Gupta, Swaib A. Lule, Maria Krutikov, Lara Gosce, Nathan Green, Jo Southern, Ambreen Imran, Robert W. Aldridge, Heinke Kunst, Marc Lipman, William Lynn, Helen Burgess, Asif Rahman, Dee Menezes, Ananna Rahman, Simon Tiberi, Peter J. White, Ibrahim Abubakar
      European Respiratory Journal 57 (6) 2003831; DOI: 10.1183/13993003.03831-2020 Published 24 June 2021
    • You have accessRestricted access
      Single-cell RNA sequencing identifies macrophage transcriptional heterogeneities in granulomatous diseases
      Shu-Yi Liao, Shaikh M. Atif, Kara Mould, Iain R. Konigsberg, Rui Fu, Elizabeth Davidson, Li Li, Andrew P. Fontenot, Lisa A. Maier, Ivana V. Yang
      European Respiratory Journal 57 (6) 2003794; DOI: 10.1183/13993003.03794-2020 Published 17 June 2021
    • Open Access
      The Severe Asthma Questionnaire: sensitivity to change and minimal clinically important difference
      Matthew Masoli, Joseph W. Lanario, Michael E. Hyland, Andrew Menzies-Gow, Adel H. Mansur, David Allen, James W. Dodd, Gemma Hayes, Jose M. Valderas, Sarah E. Lamb, Rupert C. Jones
      European Respiratory Journal 57 (6) 2100300; DOI: 10.1183/13993003.00300-2021 Published 17 June 2021
    • You have accessRestricted access
      Methacholine reactivity in lymphangioleiomyomatosis is inversely related to FEV1 and VEGF-D
      Roberto Cassandro, Davide Elia, Antonella Caminati, Gustavo Pacheco-Rodriguez, Mario Stylianou, Joel Moss, Sergio Harari
      European Respiratory Journal 57 (6) 2004270; DOI: 10.1183/13993003.04270-2020 Published 17 June 2021
    • You have accessRestricted access
      Real world effectiveness of anti-IL-5/5R therapies is independent of co-eligibility for anti-IgE therapy
      Andrew P. Hearn, Oliver D. Hug, Ziana A. Somani, Joanne Kavanagh, Grainne d'Ancona, Cris Roxas, Linda Green, Louise Thomson, Mariana Fernandes, Brian D. Kent, Jaideep Dhariwal, Alexandra M. Nanzer, David J. Jackson
      European Respiratory Journal 57 (6) 2100166; DOI: 10.1183/13993003.00166-2021 Published 10 June 2021
    • You have accessRestricted access
      Effect of corrected Global Lung Function Initiative reference equations on carbon monoxide transfer factor interpretation
      Warren R. Ruehland, Celia J. Lanteri, Pam Matsas, Danny J. Brazzale
      European Respiratory Journal 57 (6) 2004459; DOI: 10.1183/13993003.04459-2020 Published 10 June 2021
    • Open Access
      Fine particulate matter and out-of-hospital cardiac arrest of respiratory origin
      Sunao Kojima, Takehiro Michikawa, Kunihiko Matsui, Hisao Ogawa, Shin Yamazaki, Hiroshi Nitta, Akinori Takami, Kayo Ueda, Yoshio Tahara, Naohiro Yonemoto, Hiroshi Nonogi, Ken Nagao, Takanori Ikeda, Yoshio Kobayashi for the Japanese Circulation Society With Resuscitation Science Study (JCS-ReSS) Group
      European Respiratory Journal 57 (6) 2004299; DOI: 10.1183/13993003.04299-2020 Published 4 June 2021
    • You have accessRestricted access
      The role of cardiopulmonary exercise test in identifying pulmonary veno-occlusive disease
      Carmen Pérez-Olivares, Teresa Segura de la Cal, Ángela Flox-Camacho, Jorge Nuche, Jair Tenorio, Amaya Martínez Meñaca, Alejandro Cruz-Utrilla, Javier de la Cruz-Bertolo, Marte Pérez Núñez, Spanish PAH Consortium, Fernando Arribas-Ynsaurriaga, Pilar Escribano Subías
      European Respiratory Journal 57 (6) 2100115; DOI: 10.1183/13993003.00115-2021 Published 4 June 2021
  • Correspondence

    • You have accessRestricted access
      The association between inhaled corticosteroid and osteoporosis and fracture
      Cheng-Yi Wang, Chih-Cheng Lai
      European Respiratory Journal 57 (6) 2100216; DOI: 10.1183/13993003.00216-2021 Published 4 June 2021
    • You have accessRestricted access
      Pulse oximetry is an essential tool that saves lives: a call for standardisation
      Catia Cilloniz, Anita Simonds, Kjeld Hansen, Josep Alouch, Heather Zar, Yoichi Nakanishi, Stephanie Levine, Mark Cohen, Charles Dela Cruz, Scott E. Evans, Maurizio Sanguinetti, Jordi Vila, Jesús Díez Manglano, Ricard Ferrer, Lucio Criado, José Polo García, Zaira Correcher, Diana Rodriguez-Hurtado, Carmen Terrazas, Carmen Muñoz-Almagro, Carolina Garcia-Vidal, Zeina Aoun, Israel Amirav
      European Respiratory Journal 57 (6) 2100815; DOI: 10.1183/13993003.00815-2021 Published 4 June 2021
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European Respiratory Journal: 57 (6)
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