Extract
Oxidative stress is a major pathogenic driver in many diseases, and evidence to date suggests the obstructive lung disease asthma is no exception. Various lung insults, including air pollution, smoking and allergens can induce reactive oxygen species (ROS) in the lung [1].
Abstract
Pascoe et al. examine BAL samples from asthmatic patients challenged with diluent or allergen, and from patients with/without AHR, to establish the specific oxidised PCs that associate with AHR and are induced by allergic lung challenge. https://bit.ly/2TeSzH6
Footnotes
Conflict of interest: R.B. Penn has nothing to disclose.
Support statement: The work in R.B. Penn's lab is supported by NIH grants R01 HL58506, R01 AI110007, R01 HL136209, R01 AI161296, R01 HL145392, and P01 HL114471. Funding information for this article has been deposited with the Crossref Funder Registry.
- Received October 5, 2020.
- Accepted October 14, 2020.
- Copyright ©ERS 2021
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