Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • For authors
    • Instructions for authors
    • Submit a manuscript
    • Author FAQs
    • Open access
    • COVID-19 submission information
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • For authors
    • Instructions for authors
    • Submit a manuscript
    • Author FAQs
    • Open access
    • COVID-19 submission information
  • Alerts
  • Podcasts
  • Subscriptions

Impact of body mass index on development of nontuberculous mycobacterial pulmonary disease

Jin Hwa Song, Bong Seong Kim, Nakwon Kwak, Kyungdo Han, Jae-Joon Yim
European Respiratory Journal 2021 57: 2000454; DOI: 10.1183/13993003.00454-2020
Jin Hwa Song
1Dept of Internal Medicine, Veterans Health Service Medical Center, Seoul, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jin Hwa Song
Bong Seong Kim
2Dept of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nakwon Kwak
3Division of Pulmonary and Critical Care Medicine, Dept of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Nakwon Kwak
Kyungdo Han
2Dept of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Kyungdo Han
Jae-Joon Yim
3Division of Pulmonary and Critical Care Medicine, Dept of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jae-Joon Yim
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Abstract

The incidence and prevalence of nontuberculous mycobacterial pulmonary disease (NTM-PD) have been increasing worldwide. The risk of NTM-PD may be higher in undernourished populations. In this study, we tried to elucidate the impact of body mass index (BMI) and its change on development of NTM-PD.

We performed a retrospective cohort study including South Koreans aged >40 years who underwent biennial National Health Insurance System (NHIS) health check-ups in both 2005 and 2009 or 2006 and 2010. We monitored eligible individuals from the study initiation date (NHIS health check-up date in 2009 or 2010) until the diagnosis of NTM-PD or until December 31, 2017. Enroled individuals were classified based on BMI at initiation date. By calculating hazard ratios, we compared NTM-PD incidence per 100 000 person-years by BMI group and by BMI change.

A total of 5 670 229 individuals were included in the final analysis. Compared with the BMI <18.5 kg·m−2 group, the incidence of NTM-PD gradually decreased with increased BMI (adjusted hazard ratio 0.38, 95% confidence interval (CI) 0.35–0.42 for BMI 18.5–22.9; 0.17, 95% CI 0.15–0.19 for BMI 23–24.9; 0.1, 95% CI 0.09–0.11 for BMI 25–29.9; and 0.1, 95% CI 0.07–0.13 for BMI ≥30). A BMI decrease of ≥1 kg·m−2 over 4 years increased the incidence of NTM-PD (adjusted hazard ratio 1.08, 95% CI 1.01–1.16) whereas a BMI increase of ≥1 kg·m−2 decreased the incidence of NTM-PD (adjusted hazard ratio 0.77, 95% CI 0.71–0.83).

In conclusion, BMI was inversely related to development of NTM-PD and weight loss increased the risk of NTM-PD.

Abstract

Higher body mass index was protective against development of nontuberculous mycobacterial pulmonary disease (NTM-PD) among Korean people. Weight loss increased the risk of NTM-PD. https://bit.ly/2PDawxn

Footnotes

  • This article has supplementary material available from erj.ersjournals.com

  • Conflict of interest: J.H. Song has nothing to disclose.

  • Conflict of interest: B.S. Kim has nothing to disclose.

  • Conflict of interest: N. Kwak has nothing to disclose.

  • Conflict of interest: K-D. Han has nothing to disclose.

  • Conflict of interest: J-J. Yim has nothing to disclose.

  • Received February 28, 2020.
  • Accepted August 1, 2020.
  • ©ERS 2021. For reproduction rights and permissions contact permissions{at}ersnet.org
https://www.ersjournals.com/user-licence
View Full Text

ERS Members

myERS - ERS members : log in with your myERS username and password.

INDIVIDUALS

Log in Login as an individual user.

Forgot your username or password?

LIBRARY USERS

Log in through your institution

If your library has a subscription, you may already be logged in via your IP address. Otherwise you may be able to log in via one of the following routes.
You may be able to gain access using your login credentials for your institution. Contact your library if you do not have a username and password.
If your organization uses OpenAthens, you can log in using your OpenAthens username and password. To check if your institution is supported, please see this list. Contact your library for more details.
If you think you should have access, please contact your librarian or email journals@ersnet.org

Purchase access

You may purchase access to this article. This will require you to create an account if you don't already have one.
PreviousNext
Back to top
View this article with LENS
Vol 57 Issue 2 Table of Contents
European Respiratory Journal: 57 (2)
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Impact of body mass index on development of nontuberculous mycobacterial pulmonary disease
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
Alerts
Sign In to Email Alerts with your Email Address
Citation Tools
Impact of body mass index on development of nontuberculous mycobacterial pulmonary disease
Jin Hwa Song, Bong Seong Kim, Nakwon Kwak, Kyungdo Han, Jae-Joon Yim
European Respiratory Journal Feb 2021, 57 (2) 2000454; DOI: 10.1183/13993003.00454-2020

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Impact of body mass index on development of nontuberculous mycobacterial pulmonary disease
Jin Hwa Song, Bong Seong Kim, Nakwon Kwak, Kyungdo Han, Jae-Joon Yim
European Respiratory Journal Feb 2021, 57 (2) 2000454; DOI: 10.1183/13993003.00454-2020
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
Full Text (PDF)

Jump To

  • Article
    • Abstract
    • Abstract
    • Introduction
    • Materials and methods
    • Results
    • Discussion
    • Supplementary material
    • Shareable PDF
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

Subjects

  • Respiratory infections and tuberculosis
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

Original Articles

  • EmPHasis-10 as a measure of quality of life in PAH
  • EmPHasis-10 health-related quality of life score predicts outcomes in PAH
  • Periostin and airway epithelial function in asthma
Show more Original Articles

Pulmonary infection and tuberculosis

  • Multidrug- and rifampicin-resistant TB in children and adults
Show more Pulmonary infection and tuberculosis

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • CME
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Submit a manuscript
  • ERS author centre

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2021 by the European Respiratory Society