European Respiratory Journal: 57 (1)

01 January 2021; volume 57, issue 1

Editorials

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Tobacco control and the ERS: new problems and old foes
Jonathan Grigg

European Respiratory Journal 57 (1) 2003499; DOI: 10.1183/13993003.03499-2020 Published 5 January 2021
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Biomarkers in lung cancer screening: the importance of study design
David R. Baldwin, Matthew E. Callister, Philip A. Crosbie, Emma L. O'Dowd, Robert C. Rintoul, Hilary A. Robbins, Robert J.C. Steele

European Respiratory Journal 57 (1) 2004367; DOI: 10.1183/13993003.04367-2020 Published 14 January 2021
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Household air pollution and adult respiratory health
Dan Norbäck, Juan Wang

European Respiratory Journal 57 (1) 2003520; DOI: 10.1183/13993003.03520-2020 Published 14 January 2021
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Idiopathic pulmonary fibrosis: prime time for a precision-based approach to treatment with N-acetylcysteine
Anna J. Podolanczuk, Imre Noth, Ganesh Raghu

European Respiratory Journal 57 (1) 2003551; DOI: 10.1183/13993003.03551-2020 Published 5 January 2021
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Reducing Pseudomonas sputum density in bronchiectasis
Oriol Sibila

European Respiratory Journal 57 (1) 2003390; DOI: 10.1183/13993003.03390-2020 Published 5 January 2021

Task Force Report

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Imaging of pulmonary hypertension in adults: a position paper from the Fleischner Society
Martine Remy-Jardin, Christopher J. Ryerson, Mark L. Schiebler, Ann N.C. Leung, James M. Wild, Marius M. Hoeper, Philip O. Alderson, Lawrence R. Goodman, John Mayo, Linda B. Haramati, Yoshiharu Ohno, Patricia Thistlethwaite, Edwin J.R. van Beek, Shandra Lee Knight, David A. Lynch, Geoffrey D. Rubin, Marc Humbert

European Respiratory Journal 57 (1) 2004455; DOI: 10.1183/13993003.04455-2020 Published 5 January 2021

Original Articles

Lung cancer
- Open Access
  Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging
  Frank M. Sullivan, Frances S. Mair, William Anderson, Pauline Armory, Andrew Briggs, Cindy Chew, Alistair Dorward, John Haughney, Fiona Hogarth, Denise Kendrick, Roberta Littleford, Alex McConnachie, Colin McCowan, Nicola McMeekin, Manish Patel, Petra Rauchhaus, Lewis Ritchie, Chris Robertson, John Robertson, Jose Robles-Zurita, Joseph Sarvesvaran, Herbert Sewell, Michael Sproule, Thomas Taylor, Agnes Tello, Shaun Treweek, Kavita Vedhara, Stuart Schembri on behalf of the Early Diagnosis of Lung Cancer Scotland (ECLS) Team
  
  European Respiratory Journal 57 (1) 2000670; DOI: 10.1183/13993003.00670-2020 Published 14 January 2021
- Open Access
  Validation of Lung EpiCheck, a novel methylation-based blood assay, for the detection of lung cancer in European and Chinese high-risk individuals
  Mina Gaga, Joanna Chorostowska-Wynimko, Ildikó Horváth, Martin C. Tammemagi, David Shitrit, Vered H. Eisenberg, Hao Liang, David Stav, Dan Levy Faber, Maarten Jansen, Yael Raviv, Vasileios Panagoulias, Piotr Rudzinski, Gabriel Izbicki, Ohad Ronen, Adiv Goldhaber, Rawia Moalem, Nadir Arber, Ilana Haas, Qinghua Zhou
  
  European Respiratory Journal 57 (1) 2002682; DOI: 10.1183/13993003.02682-2020 Published 14 January 2021
Asthma
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  Identification of asthma phenotypes based on extrapulmonary treatable traits
  Patricia Duarte Freitas, Rafaella França Xavier, Vanessa Marie McDonald, Peter Gerard Gibson, Laura Cordova-Rivera, Karina Couto Furlanetto, Joice Mara de Oliveira, Regina Maria Carvalho-Pinto, Alberto Cukier, Rafael Stelmach, Celso Ricardo Fernandes Carvalho
  
  European Respiratory Journal 57 (1) 2000240; DOI: 10.1183/13993003.00240-2020 Published 21 January 2021
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  Incidence of osteoporosis and fragility fractures in asthma: a UK population-based matched cohort study
  Christos V. Chalitsios, Tricia M. McKeever, Dominick E. Shaw
  
  European Respiratory Journal 57 (1) 2001251; DOI: 10.1183/13993003.01251-2020 Published 21 January 2021
Asthma and pollution
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  Exposure to household air pollution over 10 years is related to asthma and lung function decline
  Xin Dai, Dinh S. Bui, Jennifer L. Perret, Adrian J. Lowe, Peter A. Frith, Gayan Bowatte, Paul S. Thomas, Graham G. Giles, Garun S. Hamilton, Helen Tsimiklis, Jennie Hui, John Burgess, Aung K. Win, Michael J. Abramson, E. Haydn Walters, Shyamali C. Dharmage, Caroline J. Lodge
  
  European Respiratory Journal 57 (1) 2000602; DOI: 10.1183/13993003.00602-2020 Published 14 January 2021
Asthma and paediatrics
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  Maternal antibiotic use during pregnancy and asthma in children: population-based cohort study and sibling design
  Natalie C. Momen, Xiaoqin Liu
  
  European Respiratory Journal 57 (1) 2000937; DOI: 10.1183/13993003.00937-2020 Published 14 January 2021
Interstitial lung disease
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  Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised trial
  Susumu Sakamoto, Kensuke Kataoka, Yasuhiro Kondoh, Motoyasu Kato, Masaki Okamoto, Hiroshi Mukae, Masashi Bando, Takafumi Suda, Kazuhiro Yatera, Yoshinori Tanino, Tomoo Kishaba, Noboru Hattori, Yoshio Taguchi, Takefumi Saito, Yasuhiko Nishioka, Kazuyoshi Kuwano, Kazuma Kishi, Naohiko Inase, Shinichi Sasaki, Hajime Takizawa, Takeshi Johkoh, Fumikazu Sakai, Sakae Homma the Diffuse Lung Diseases Research Group of the Ministry of Health, Labour and Welfare, Japan
  
  European Respiratory Journal 57 (1) 2000348; DOI: 10.1183/13993003.00348-2020 Published 5 January 2021
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  Exhaled breath analysis by use of eNose technology: a novel diagnostic tool for interstitial lung disease
  Catharina C. Moor, Judith C. Oppenheimer, Gizal Nakshbandi, Joachim G.J.V. Aerts, Paul Brinkman, Anke-Hilse Maitland-van der Zee, Marlies S. Wijsenbeek
  
  European Respiratory Journal 57 (1) 2002042; DOI: 10.1183/13993003.02042-2020 Published 5 January 2021
Interstitial lung disease and basic science
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  NADPH oxidase DUOX1 sustains TGF-β1 signalling and promotes lung fibrosis
  Ruy Andrade Louzada, Raphaël Corre, Rabii Ameziane El Hassani, Lydia Meziani, Madeleine Jaillet, Aurélie Cazes, Bruno Crestani, Eric Deutsch, Corinne Dupuy
  
  European Respiratory Journal 57 (1) 1901949; DOI: 10.1183/13993003.01949-2019 Published 14 January 2021
Acute lung injury and basic science
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  Oestrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation
  Lasti Erfinanda, Krishnan Ravindran, Franziska Kohse, Kathleen Gallo, Robert Preissner, Thomas Walther, Wolfgang M. Kuebler
  
  European Respiratory Journal 57 (1) 2000921; DOI: 10.1183/13993003.00921-2020 Published 21 January 2021
Bronchiectasis
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  Efficacy and safety of TOBI Podhaler in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study
  Michael R. Loebinger, Eva Polverino, James D. Chalmers, Harm A.W.M. Tiddens, Herman Goossens, Michael Tunney, Felix C. Ringshausen, Adam T. Hill, Rashidkhan Pathan, Gerhild Angyalosi, Francesco Blasi, Stuart J. Elborn, Charles S. Haworth on behalf of the iBEST-1 Trial Team
  
  European Respiratory Journal 57 (1) 2001451; DOI: 10.1183/13993003.01451-2020 Published 5 January 2021
Cystic fibrosis
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  Hyperglycaemia in cystic fibrosis adversely affects BK channel function critical for mucus clearance
  Charles D. Bengtson, Michael D. Kim, Abeer Anabtawi, Jianghua He, John S. Dennis, Sara Miller, Makoto Yoshida, Nathalie Baumlin, Matthias Salathe
  
  European Respiratory Journal 57 (1) 2000509; DOI: 10.1183/13993003.00509-2020 Published 14 January 2021
Cystic fibrosis and basic science
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  Correction of CFTR function in intestinal organoids to guide treatment of cystic fibrosis
  Anabela S. Ramalho, Eva Fürstová, Annelotte M. Vonk, Marc Ferrante, Catherine Verfaillie, Lieven Dupont, Mieke Boon, Marijke Proesmans, Jeffrey M. Beekman, Ifat Sarouk, Carlos Vazquez Cordero, Francois Vermeulen, Kris De Boeck on behalf of the Belgian Organoid Project
  
  European Respiratory Journal 57 (1) 1902426; DOI: 10.1183/13993003.02426-2019 Published 5 January 2021
Thoracic sugery
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  Automated closed-loop versus standard manual oxygen administration after major abdominal or thoracic surgery: an international multicentre randomised controlled study
  Erwan L'Her, Samir Jaber, Daniel Verzilli, Christophe Jacob, Brigitte Huiban, Emmanuel Futier, Thomas Kerforne, Victoire Pateau, Pierre-Alexandre Bouchard, Maëlys Consigny, François Lellouche
  
  European Respiratory Journal 57 (1) 2000182; DOI: 10.1183/13993003.00182-2020 Published 5 January 2021
Tuberculosis
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  High rifampicin-resistant TB cure rates and prevention of severe ototoxicity after replacing the injectable by linezolid in early stage of hearing loss
  Mahamadou Bassirou Souleymane, Alberto Piubello, Ibrahim Mamane Lawan, Souleymane Hassane-Harouna, Mourtala Mohamed Assao-Neino, Alphazazi Soumana, Zelika Hamidou-Harouna, Assiatou Gagara-Issoufou, Nimer Ortuño-Gutiérrez, Alberto Roggi, Valerie Schwoebel, Saïdou Mamadou, Lutgarde Lynen, Bouke De Jong, Armand Van Deun, Tom Decroo
  
  European Respiratory Journal 57 (1) 2002250; DOI: 10.1183/13993003.02250-2020 Published 21 January 2021
- Open Access
  Use of a whole genome sequencing-based approach for Mycobacterium tuberculosis surveillance in Europe in 2017–2019: an ECDC pilot study
  Elisa Tagliani, Richard Anthony, Thomas A. Kohl, Albert de Neeling, Vlad Nikolayevskyy, Csaba Ködmön, Florian P. Maurer, Stefan Niemann, Dick van Soolingen, Marieke J. van der Werf, Daniela Maria Cirillo on behalf of the ECDC molecular surveillance project participants
  
  European Respiratory Journal 57 (1) 2002272; DOI: 10.1183/13993003.02272-2020 Published 5 January 2021

State of the Art

Open Access
E-cigarette use and respiratory disorders: an integrative review of converging evidence from epidemiological and laboratory studies
Thomas A. Wills, Samir S. Soneji, Kelvin Choi, Ilona Jaspers, Elizabeth K. Tam

European Respiratory Journal 57 (1) 1901815; DOI: 10.1183/13993003.01815-2019 Published 21 January 2021

Series

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Treatment options in type-2 low asthma
Timothy S.C. Hinks, Stewart J. Levine, Guy G. Brusselle

European Respiratory Journal 57 (1) 2000528; DOI: 10.1183/13993003.00528-2020 Published 21 January 2021

Review

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Sleep-related breathing disorders and pulmonary hypertension
Yochai Adir, Marc Humbert, Ari Chaouat

European Respiratory Journal 57 (1) 2002258; DOI: 10.1183/13993003.02258-2020 Published 5 January 2021

Agora

Research letters
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  Serum mitochondrial DNA predicts the risk of acute exacerbation and progression of idiopathic pulmonary fibrosis
  Koji Sakamoto, Taiki Furukawa, Yasuhiko Yamano, Kensuke Kataoka, Ryo Teramachi, Anjali Walia, Atsushi Suzuki, Masahide Inoue, Yoshio Nakahara, Changwan Ryu, Naozumi Hashimoto, Yasuhiro Kondoh
  
  European Respiratory Journal 57 (1) 2001346; DOI: 10.1183/13993003.01346-2020 Published 21 January 2021
- Open Access
  Ivacaftor modifies cystic fibrosis neutrophil phenotype in subjects with R117H residual function CFTR mutations
  Gareth R. Hardisty, Sheonagh M. Law, Suzanne Carter, Brenda Grogan, Pradeep K. Singh, Edward F. McKone, Robert D. Gray
  
  European Respiratory Journal 57 (1) 2002161; DOI: 10.1183/13993003.02161-2020 Published 21 January 2021
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  Chronic thromboembolic pulmonary hypertension and totally implantable central venous access systems
  Mitja Jevnikar, David Montani, Laurent Savale, Andrei Seferian, Etienne-Marie Jutant, Athénaïs Boucly, Mariana Preda, Jason Weatherald, Sophie Bulifon, Florence Parent, Philippe Brenot, Elie Fadel, Olivier Sitbon, Gérald Simonneau, Marc Humbert, Xavier Jaïs
  
  European Respiratory Journal 57 (1) 2002208; DOI: 10.1183/13993003.02208-2020 Published 21 January 2021
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  Effect of type and dosage of newly prescribed inhaled corticosteroids on obstructive lung disease and pneumonia hospitalisations in older individuals with asthma, COPD or both: a retrospective study of health administrative data
  Tetyana Kendzerska, Shawn D. Aaron, Teresa To, Chris Licskai, Matthew B. Stanbrook, Mary-Ellen Hogan, Wan C. Tan, Jean Bourbeau, Andrea S. Gershon for the Canadian Respiratory Research Network and CanBREATHE (the Canadian Best Respiratory Research Evaluation and Analyst Team of Health Experts)
  
  European Respiratory Journal 57 (1) 2002585; DOI: 10.1183/13993003.02585-2020 Published 14 January 2021
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  Omalizumab restores the ability of human plasmacytoid dendritic cells to induce Foxp3⁺Tregs
  Jacobo López-Abente, Cristina Benito-Villalvilla, Xavier Jaumont, Pascal Pfister, Paolo Tassinari, Oscar Palomares
  
  European Respiratory Journal 57 (1) 2000751; DOI: 10.1183/13993003.00751-2020 Published 14 January 2021
- Open Access
  Genetically proxied interleukin-6 receptor inhibition: opposing associations with COVID-19 and pneumonia
  Susanna C. Larsson, Stephen Burgess, Dipender Gill
  
  European Respiratory Journal 57 (1) 2003545; DOI: 10.1183/13993003.03545-2020 Published 14 January 2021
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  Rapid genomic first- and second-line drug resistance prediction from clinical Mycobacterium tuberculosis specimens using Deeplex-MycTB
  Silke Feuerriegel, Thomas A. Kohl, Christian Utpatel, Sönke Andres, Florian P. Maurer, Jan Heyckendorf, Agathe Jouet, Nelly Badalato, Lynda Foray, Rashidatu Fouad Kamara, Osman S. Conteh, Philip Supply, Stefan Niemann
  
  European Respiratory Journal 57 (1) 2001796; DOI: 10.1183/13993003.01796-2020 Published 5 January 2021
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  Pragmatic global dosing recommendations for the 3-month, once-weekly rifapentine and isoniazid preventive TB regimen in children
  Kendra K. Radtke, Jennifer E. Hibma, Anneke C. Hesseling, Rada M. Savic
  
  European Respiratory Journal 57 (1) 2001756; DOI: 10.1183/13993003.01756-2020 Published 5 January 2021
- Open Access
  Impact of the COVID-19 pandemic on tuberculosis laboratory services in Europe
  Vladyslav Nikolayevskyy, Yen Holicka, Dick van Soolingen, Marieke J. van der Werf, Csaba Ködmön, Elena Surkova, Doris Hillemann, Ramona Groenheit, Daniela Cirillo
  
  European Respiratory Journal 57 (1) 2003890; DOI: 10.1183/13993003.03890-2020 Published 5 January 2021
Correspondence
- Open Access
  Increased focus on non-animal models for COVID-19 and non-COVID lung research
  Laura Gribaldo, Killian Hurley, Pieter Hiemstra, Catherine Greene
  
  European Respiratory Journal 57 (1) 2004267; DOI: 10.1183/13993003.04267-2020 Published 14 January 2021
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  User-life of ICS/LABA inhaler devices should be considered when prescribed as relievers
  Roy A. Pleasants, Stephen L. Tilley, Anthony J. Hickey, Omar S. Usmani
  
  European Respiratory Journal 57 (1) 2003921; DOI: 10.1183/13993003.03921-2020 Published 14 January 2021
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  Similar distribution of peripheral blood eosinophil counts in European and East Asian populations from investigations of large-scale general population studies: the Nagahama Study
  Hironobu Sunadome, Susumu Sato, Hisako Matsumoto, Kimihiko Murase, Takahisa Kawaguchi, Yasuharu Tabara, Kazuo Chin, Fumihiko Matsuda, Toyohiro Hirai
  
  European Respiratory Journal 57 (1) 2004101; DOI: 10.1183/13993003.04101-2020 Published 5 January 2021

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Table of Contents

Editorials

Task Force Report

Original Articles

Lung cancer

Asthma

Asthma and pollution

Asthma and paediatrics

Interstitial lung disease

Interstitial lung disease and basic science

Acute lung injury and basic science

Bronchiectasis

Cystic fibrosis

Cystic fibrosis and basic science

Thoracic sugery

Tuberculosis

State of the Art

Series

Review

Agora

Research letters

Correspondence

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