Abstract
Background: The forced expiratory volume in 1s (FEV1) falls steadily in healthy people over the age of 40 by 22.4 ml per year (Thomas, E. at al., BMJ Open 2019; 9: 63-78) as well as in the patients with chronic obstructive pulmonary disease (COPD) III – IV GOLD by 35-59 ml per year (Tantucci, C. et al., International Journal of Chronic Obstructive Pulmonary disease 2012, 7: 95-99).
The aim of the study was to detect whether spirometry parameters change in case of increase of adherence to treatment.
Methods: The 156 patients were included into study. The study consisted of 5 visits and its duration was 12 months. At each visit spirometry was performed and the patients were trained to use inhaler due to COPD correctly. The short structured discussion was conducted with the patients.
The comparison of parameters average values and reliability assessment of intergroup differences was conducted using T-test for independent samples and T-test for dependent samples. The statistical software package SPSS 21.0 was used for these purposes.
Results: The adherence to COPD treatment raised from 44.41 ± 1.07% to 75.21 ± 0.78% (p <0.001). The adherence to treatment improvement had positive influence on some spirometry parameters. They are forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and forced expiratory volume in 6 s (FEV 6). So, FEV1 increased by 20 ml (1.16%, p=0.007), FVC by 90 ml (2.22%, p< 0.001) and FEV 6 by 50 ml (1.96%, p=0.002).
Conclusion: In case of adherence to COPD treatment improve FEV1, FVC and FEV6 do not fall and even raised slightly but statistically significant.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 634.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020