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Maternal and perinatal obesity arrests alveolarization and reduces alveolar progenitor cells in offspring

Jaco Selle, Katharina Dinger, Hanan Kesler, Theodoros Georgomanolis, Christina Vohlen, Rebecca Wilke, Jörg Dötsch, Miguel A. Alejandre Alcazar
European Respiratory Journal 2020 56: 5241; DOI: 10.1183/13993003.congress-2020.5241
Jaco Selle
1University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Comparative Medicine, Center for Molecular Medicine Cologne (CMMC), Germany, Cologne, Germany
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  • For correspondence: jaco.selle@uk-koeln.de
Katharina Dinger
1University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Comparative Medicine, Center for Molecular Medicine Cologne (CMMC), Germany, Cologne, Germany
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Hanan Kesler
2University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
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Theodoros Georgomanolis
3University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne Center for Genomics (CCG), Cologne, Germany
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Christina Vohlen
4University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
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Rebecca Wilke
2University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
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Jörg Dötsch
5University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
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Miguel A. Alejandre Alcazar
6University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany; 2University of Cologne, Faculty of Medicine and University Hospital Cologne, Comparative Medicine, Center for Molecular Medicine Cologne (CMMC), Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
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Article Information

vol. 56 no. suppl 64
DOI 
https://doi.org/10.1183/13993003.congress-2020.5241

Published By 
European Respiratory Society
Print ISSN 
0903-1936
Online ISSN 
1399-3003
History 
  • Published online October 28, 2020.

Copyright & Usage 
Copyright ©the authors 2020

Author Information

  1. Jaco Selle1⇑,
  2. Katharina Dinger1,
  3. Hanan Kesler2,
  4. Theodoros Georgomanolis3,
  5. Christina Vohlen4,
  6. Rebecca Wilke2,
  7. Jörg Dötsch5 and
  8. Miguel A. Alejandre Alcazar6
  1. 1University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Comparative Medicine, Center for Molecular Medicine Cologne (CMMC), Germany, Cologne, Germany
  2. 2University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
  3. 3University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne Center for Genomics (CCG), Cologne, Germany
  4. 4University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
  5. 5University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
  6. 6University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany; 2University of Cologne, Faculty of Medicine and University Hospital Cologne, Comparative Medicine, Center for Molecular Medicine Cologne (CMMC), Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatric and Adolescent Medicine, Germany, Cologne, Germany
  1. Jaco Selle, University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Experimental Pediatrics - Experimental Pulmonology, Department of Pediatric and Adolescent Medicine, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Comparative Medicine, Center for Molecular Medicine Cologne (CMMC), Germany, Cologne, Germany. E-mail: jaco.selle{at}uk-koeln.de

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Maternal and perinatal obesity arrests alveolarization and reduces alveolar progenitor cells in offspring
Jaco Selle, Katharina Dinger, Hanan Kesler, Theodoros Georgomanolis, Christina Vohlen, Rebecca Wilke, Jörg Dötsch, Miguel A. Alejandre Alcazar
European Respiratory Journal Sep 2020, 56 (suppl 64) 5241; DOI: 10.1183/13993003.congress-2020.5241

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Maternal and perinatal obesity arrests alveolarization and reduces alveolar progenitor cells in offspring
Jaco Selle, Katharina Dinger, Hanan Kesler, Theodoros Georgomanolis, Christina Vohlen, Rebecca Wilke, Jörg Dötsch, Miguel A. Alejandre Alcazar
European Respiratory Journal Sep 2020, 56 (suppl 64) 5241; DOI: 10.1183/13993003.congress-2020.5241
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