Abstract
Rationale: Comorbidities play an important role in the progression from latent tuberculosis (TB) to active TB. Management of comorbidities is one of the four components of Pillar “Integrated, patient-centred care and prevention” of the End TB Strategy. The study of the relative risks of TB in adolescents with comorbidities is relevant and important for TB screening of the adolescent’s population and TB control.
The aim of this study was to calculate the relative risk of pulmonary TB in adolescents with comorbidities.
Methods: For this study, a database was developed where 317 primary cases of pulmonary TB among adolescents living in Belarus were recorded. All comorbidities in adolescents of the analyzed group were studied. The official census data of the National Statistical Committee of the Republic of Belarus for the adolescent’s population inhabiting in Belarus were used for calculating relative risk of pulmonary TB. The general formula for the relative risk, using a 2x2 table, has been applied.
Results: The highest relative risk of pulmonary TB was observed in adolescents, often suffering from acute respiratory viral infections: 10.9 [CI = 6.8 – 17.7]. The relative risk of TB in adolescents with pediatric infectious diseases was 3.6 [CI = 2.1 – 6.0]. The relative risk of TB in adolescents with acute bronchitis was slightly lower – 3.3 [CI = 1.9 – 5.6]. The relative risk of TB in adolescents with digestive system diseases was lower and amounted to 2.6 [CI = 1.5 – 4.4].
Conclusion: The results obtained show the need for TB screening in adolescents, often suffering from acute respiratory viral infections, pediatric infectious diseases, acute bronchitis, digestive system diseases.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 488.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020