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Impact of a multimodal telemonitoring intervention on CPAP adherence in symptomatic low-cardiovascular risk sleep apnea: a randomized controlled trial

Renaud Tamisier, Erika Treptow, Marie Joyeux-Faure, Patrick Lévy, Marc Sapène, Meriem Benmerad, Sébastien Bailly, Yves Grillet, Bruno Stach, Jean-François Muir, Hervé Pegliasco, Jean-Louis Pépin
European Respiratory Journal 2020 56: 4739; DOI: 10.1183/13993003.congress-2020.4739
Renaud Tamisier
1Univ. Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, 38000 Grenoble, France, Grenoble, France
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  • For correspondence: rtamisier@chu-grenoble.fr
Erika Treptow
1Univ. Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, 38000 Grenoble, France, Grenoble, France
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Marie Joyeux-Faure
1Univ. Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, 38000 Grenoble, France, Grenoble, France
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Patrick Lévy
1Univ. Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, 38000 Grenoble, France, Grenoble, France
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Marc Sapène
2Private practice sleep and respiratory disease center, Nouvelle Clinique Bel Air, Bordeaux, France, Bordeaux, France
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Meriem Benmerad
1Univ. Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, 38000 Grenoble, France, Grenoble, France
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Sébastien Bailly
1Univ. Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, 38000 Grenoble, France, Grenoble, France
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Yves Grillet
3Private practice sleep and respiratory disease center, Valence, France, Valence, France
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Bruno Stach
4Private practice sleep and respiratory disease center, Valenciennes, France, Valencienne, France
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Jean-François Muir
5Rouen University Hospital, Bois Guillaume, France, Bois Guillaume, France
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Hervé Pegliasco
6Private practice sleep and respiratory disease center, Marseille, France , Marseille, France
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Jean-Louis Pépin
1Univ. Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, 38000 Grenoble, France, Grenoble, France
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Abstract

Background: One of the major challenges in treating obstructive sleep apnea (OSA) is to achieve adequate continuous positive airway pressure (CPAP) adherence. We determined the effect of a multimodal telemonitoring intervention on CPAP adherence, quality of life and functional status in symptomatic OSA patients with low cardiovascular risk.

Study Design and Methods: In a multicenter, randomized controlled trial, newly diagnosed OSA patients were randomly assigned to multimodal telemonitoring(TM) for 6 months vs usual care (UC). TMconsisted ofbuilt-in electronic alert algorithms for early adjustment of CPAP treatment in case of side effects, leaks or persistent residual events.The outcomesincluded CPAP adherence, daily symptoms such as fatigue and sleepiness, and quality of life.

Results: Of 206 OSA patients aged 50.6 [42.1;58.1] (median [IQR]) years;predominantly male (63%) with body mass index of 30.6 [26.8;35.1] kg/m2and an AHI of 45.2 [34.0;60.0] events/hour) 102 received UC and 104 TM. After 6 months of treatment, CPAPadherence was similar in the two groups when assessed either by mean duration of usage (4.73±2.48 hours/night in the TM group and 5.08±2.44 hours/night in the UC group, p=0.30) or in % of patients adherent to treatment (over 4 hours usage/night, > 70% nights; 64% in TM vs 72% in UC, p=0.24). There was no significant difference between the groups in effect size of improvement in fatigue and sleepiness.

Interpretation: In severe OSA patients with low cardiovascular risk, multimodal telemonitoring did not increase CPAP adherence. For both TM and UC groups similar improvements in daytime symptoms were achieved.

  • Apnoea / Hypopnea
  • Monitoring
  • Telemedicine

Footnotes

Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 4739.

This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2020
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Impact of a multimodal telemonitoring intervention on CPAP adherence in symptomatic low-cardiovascular risk sleep apnea: a randomized controlled trial
Renaud Tamisier, Erika Treptow, Marie Joyeux-Faure, Patrick Lévy, Marc Sapène, Meriem Benmerad, Sébastien Bailly, Yves Grillet, Bruno Stach, Jean-François Muir, Hervé Pegliasco, Jean-Louis Pépin
European Respiratory Journal Sep 2020, 56 (suppl 64) 4739; DOI: 10.1183/13993003.congress-2020.4739

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Impact of a multimodal telemonitoring intervention on CPAP adherence in symptomatic low-cardiovascular risk sleep apnea: a randomized controlled trial
Renaud Tamisier, Erika Treptow, Marie Joyeux-Faure, Patrick Lévy, Marc Sapène, Meriem Benmerad, Sébastien Bailly, Yves Grillet, Bruno Stach, Jean-François Muir, Hervé Pegliasco, Jean-Louis Pépin
European Respiratory Journal Sep 2020, 56 (suppl 64) 4739; DOI: 10.1183/13993003.congress-2020.4739
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  • The effect of CPAP on quality of life in patients with ‘very’ mild Obstructive Sleep Apnoea (OSA): Results from a subset of the MERGE Randomised Trial
  • Clinical and polysomnographic determinants of REM predominant obstructive sleep apnoea and response to treatment in a revascularized coronary artery disease cohort
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