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BAP1 loss predicts longer survival for mesothelioma patients treated with pemetrexed-based chemotherapy

Vasiliki Panou, Amber Louw, Weronika Maria Szejniuk, Christos Meristoudis, Siaw Ming Chai, Louise Lynggård Andersen, Azadeh Birbaneh Asghari, Mogens Vyberg, Johnni Hansen, Jenette Creaney, Oluf Dimitri Røe
European Respiratory Journal 2020 56: 4490; DOI: 10.1183/13993003.congress-2020.4490
Vasiliki Panou
1Department of Respiratory Medicine, Odense University Hospital & Department of Respiratory Diseases, Aalborg University Hospital, Odense & Aalborg, Denmark
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  • For correspondence: vasiliki_panou@hotmail.com
Amber Louw
2PathWest Laboratory Medicine, QEII Medical Centre & Edith Cowan University, Perth, Australia
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Weronika Maria Szejniuk
3Department of Oncology, Aalborg, Denmark
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Christos Meristoudis
4Institute of Pathology, Aalborg, Denmark
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Siaw Ming Chai
5Division of Anatomical Pathology, QEII Medical Centre PathWest Laboratory Medicine , Perth, Australia
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Louise Lynggård Andersen
4Institute of Pathology, Aalborg, Denmark
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Azadeh Birbaneh Asghari
4Institute of Pathology, Aalborg, Denmark
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Mogens Vyberg
6Aalborg University, Aalborg, Denmark
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Johnni Hansen
7Danish Cancer Society, Copenhagen, Denmark
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Jenette Creaney
8National Centre for Asbestos Related Disease, Centre for Respiratory Health, University of Western Australia & Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Perth, Australia
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Oluf Dimitri Røe
9Cancer Clinic, Levanger Hospital, Nord-Trøndelag Health Trust & Department of Clinical and Molecular Medicine, Levanger & Trondheim, Norway
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  • Pemetrexed group
    N=77
    BSC group
    N=91
    P-value
    BAP1-N=58N=44<0.01
    MaleN=68N=740.29
    Epithelioid subtypeN=48N=500.75
    Age (years,median,IQR)71(12)75(15)0.06
    PS:0,1N=68N=50<0.01
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BAP1 loss predicts longer survival for mesothelioma patients treated with pemetrexed-based chemotherapy
Vasiliki Panou, Amber Louw, Weronika Maria Szejniuk, Christos Meristoudis, Siaw Ming Chai, Louise Lynggård Andersen, Azadeh Birbaneh Asghari, Mogens Vyberg, Johnni Hansen, Jenette Creaney, Oluf Dimitri Røe
European Respiratory Journal Sep 2020, 56 (suppl 64) 4490; DOI: 10.1183/13993003.congress-2020.4490

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BAP1 loss predicts longer survival for mesothelioma patients treated with pemetrexed-based chemotherapy
Vasiliki Panou, Amber Louw, Weronika Maria Szejniuk, Christos Meristoudis, Siaw Ming Chai, Louise Lynggård Andersen, Azadeh Birbaneh Asghari, Mogens Vyberg, Johnni Hansen, Jenette Creaney, Oluf Dimitri Røe
European Respiratory Journal Sep 2020, 56 (suppl 64) 4490; DOI: 10.1183/13993003.congress-2020.4490
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