Abstract
Introduction: Early diagnosis of IPF is needed,but except the role of primary care physicians to suspect-detect early signs-symptoms and the radiologists' warning of incidental finding of ILD at HCRT preformed for other reason,there´s no screening program to promote the early detection.
Aims: evaluate cost-effectiveness of implementing an active program to screen new ILD cases in early stages among relatives of IPF patients.
Methods: Jan.2017-Sept.2019,first-degree relatives >40 years,of patients with IPF,assisted in Basque Health Service´s ILD Units,were invited to participate.Demographic and clinical variables were collected.Patients underwent:functional respiratory Test,6-min walking test and HRCT.
Results: 164 relatives of 94 IPF index cases were studied (results are summarized in figure 1).
Cluster analysis divided sample in 3 groups (fig.2)
Conclusions:
FPF affects 31.9% families of patients initially diagnosed as sporadic IPF.
47.8% of siblings has fibrosing disease.
Cluster analysis identified 3 groups:(a)healthy,(b)IPF and(c)fibrotic ILA-Inconsistent with NIU.
Study of relatives of the same generation as IPF patients could be useful as ILD screening.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 447.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020
