Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions

Acute health effects after passive e-vape among patients with COPD – an RCT exposure study

Karin Rosenkilde Laursen, Jakob H. Bønløkke, Merete Bilde, Marianne Glasius, Elisabeth Bendstrup, Søren K. Kjærgaard, Anna-Carin Olin, Torben Sigsgaard
European Respiratory Journal 2020 56: 4387; DOI: 10.1183/13993003.congress-2020.4387
Karin Rosenkilde Laursen
1Section of Environment, Occupation and Health, Department of Public Health, Aarhus University, Aarhus, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: krl@ph.au.dk
Jakob H. Bønløkke
2Danish Ramazzini Centre, Department of Occupational and Environmental Medicine, Aalborg University Hospital, Ålborg, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Merete Bilde
3Department of Chemistry, Aarhus University, Aarhus, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marianne Glasius
3Department of Chemistry, Aarhus University, Aarhus, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elisabeth Bendstrup
4Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Søren K. Kjærgaard
1Section of Environment, Occupation and Health, Department of Public Health, Aarhus University, Aarhus, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anna-Carin Olin
5Department of Public Health and Community Medicine, University of Gothenburg, Gothenburg, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Torben Sigsgaard
1Section of Environment, Occupation and Health, Department of Public Health, Aarhus University, Aarhus, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
Loading

Abstract

Background: E-cigarette use is dramatically increasing and often permitted in smoke-free areas causing passive vape exposure. Little is known about potential adverse health effects of passive vape and people with respiratory diseases may be more susceptible. Our aim was to investigate local and systemic effects of short-term passive exposure to vape among patients with mild or moderate COPD.

Methods: In a randomised double-blinded crossover study non-smoking COPD patients were exposed for four hours at two different exposure conditions separated by 14 days; A) clean filtered air (particles concentration <6 µg/m3) and B) passive vaping (median: 18 µg/m3 (range: 8-333)). E-cigarette users in an adjacent chamber were vaping in situation B and vape-polluted air was passed to the exposure chamber. Health effects including FEV1/FVC, FeNO, Surfactant Protein-A (SP-A) in Particles in Exhaled Air (PExA) and plasma biomarkers were evaluated before, after, and 24 h. after exposures.

Results: 16 patients (mean age 68) participated. Exposure to passive vape did not alter FEV1/FVC or FeNO. SP-A in exhaled air was negatively affected by time and exposure to vape, and some plasma biomarkers (citrate, phospholipids and free cholesterol in very large HDL plus triglycerides in medium HDL) increased significantly after exposure to vape alone.

Conclusions: At the exposure levels in the study, SP-A in exhaled particles, citrate and some plasma biomarkers in patients with COPD were affected by passive vaping indicating inflammation and atherogene activity. We recommend that passive vape exposure should be further studied.

  • Air pollution
  • Systemic effect
  • Experimental approaches

Footnotes

Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 4387.

This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2020
Previous
Back to top
Vol 56 Issue suppl 64 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Acute health effects after passive e-vape among patients with COPD – an RCT exposure study
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Acute health effects after passive e-vape among patients with COPD – an RCT exposure study
Karin Rosenkilde Laursen, Jakob H. Bønløkke, Merete Bilde, Marianne Glasius, Elisabeth Bendstrup, Søren K. Kjærgaard, Anna-Carin Olin, Torben Sigsgaard
European Respiratory Journal Sep 2020, 56 (suppl 64) 4387; DOI: 10.1183/13993003.congress-2020.4387

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Acute health effects after passive e-vape among patients with COPD – an RCT exposure study
Karin Rosenkilde Laursen, Jakob H. Bønløkke, Merete Bilde, Marianne Glasius, Elisabeth Bendstrup, Søren K. Kjærgaard, Anna-Carin Olin, Torben Sigsgaard
European Respiratory Journal Sep 2020, 56 (suppl 64) 4387; DOI: 10.1183/13993003.congress-2020.4387
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo

Jump To

  • Article
  • Info & Metrics
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Asthma do not counteract smoking initiation
  • Outpatient smoking cessation: preliminary findings of a non-inferiority RCT comparing blended with face-to-face delivery mode
  • Late Breaking Abstract - Differences in flavorant levels and synthetic coolant use between USA, EU and Canadian Juul products
Show more Tobacco, smoking control and health educ.

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2022 by the European Respiratory Society