Abstract
Introduction: Lung emphysema is associated with high morbidity and mortality rates. Both surgical lung volume reduction (LVRS) and endoscopic lung volume reduction with valves (ELVR-V) seem to produce good clinical outcomes.However, a systematical comparison of different treatment approaches is still missing. The main goal of the Lung Emphysema Registry (LE-R) is to analyze types of treatment applied to patients with severe lung emphysema and to describe outcomes in relation to treatment techniques over time.
Methods: The LE-R is a multicenter non-randomized prospective clinical study, which is collecting data exclusively on patients with lung emphysema treated at specialized centers. The patients were followed up after 3 months, and the lung function (FEV1, RV, VC, DLCO), the clinical status, quality of life (CAT and mMRC) and exercise capacity (6-MWT) were documented.
Results: Since 2017 246 patients were included. Table 1 displays improvements in lung function and quality of life in both groups at 3mo FU.
Conclusions: These novel findings suggest that both techniques are beneficial to patients with severe emphysema up to 3 months after intervention in a real-world observational study. Future analyses might help to define which treatment types should be applied to the specific patients subgroups.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 4095.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020