Abstract
The effect of exercise-based interventions, such as pulmonary rehabilitation, in interstitial lung diseases (ILD) is unclear. Reasons include inadequate reports of studies’ methods, which make the interpretation of results across trials challenging. A core outcome set to be used in clinical trials enrolling patients with ILD was published in 2014 (Saketkoo et al. Thorax, 2014, 69.5: 436-44). However, its use by trials in exercise-based interventions is unknown. We reviewed the outcomes most used in clinical trials exploring exercise-based interventions in ILD.
Pubmed, Web of Science, Scopus and EBSCO were searched until August 2019. Randomized controlled trials exploring the effects of exercise-based interventions in patients with ILD were included. Title, abstract and full text were screened by 2 researchers independently and consensus was reached.
The search strategy resulted in 10010 possibly eligible articles. After comprehensive screening, 15 were withheld for data extraction. Patient-reported and clinical outcomes and measures found are in figure 1.
Inconsistencies between the core outcome set and trials’ reports were found for the use of imaging (recommended-not used), exercise tolerance (used-not recommended) and cough (recommended-not used) outcomes and measures. A specific core outcome set for clinical trials exploring exercise-based interventions, including pulmonary rehabilitation, in patients with ILD may be needed.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3235.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020