Abstract
Objective: COPD is positioned as a systemic inflammatory disease. In COPD patients, arteriosclerosis is important as a risk factor for cerebral infarction and myocardial infarction. Recent studies have reported that elderly asthma and eosinophilia were risk factors for atherosclerosis. Previous reports have shown that the prognosis of COPD patients with asthma was worse than COPD patients without asthma. In this study, we compared the data of Max-IMT as an arteriosclerosis index between COPD patients with and without asthma.
Methods: The subjects were 68 COPD patients with a history of severe smoking. According to the severity classification, GOLD 1 was 14 people, GOLD 2 was 29 people, GOLD 3 was 18 people, and GOLD 4 was 7 people. There are 38 COPD patients without asthma (G1, male 26, female 12) and 30 COPD patients with asthma (G2, male 19, female 11). Based on informed consent, the measurement of Max-IMT was performed and analyzed.
Results: Regarding the Max-IMT (mean ± SE), G1 was 1.46 ± 0.48 mm and G2 was 1.38 ± 0.55 mm, and no significant difference was observed between the two groups (P = 0.07).
Conclusion: Previous studies have shown that the prognosis of COPD patients with asthma was poor. However, it is still controversial in this point. At least in the present study, the results showed there was no significant difference in Max-IMT between the two groups, indicating that there was no significant difference in the risk of arteriosclerosis. In the future, it is necessary to compare arteriosclerosis with or without asthma in severe COPD.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3224.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020