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Smoking status and in-hospital outcomes of ST elevation myocardial infarction patients in a Brazilian public university hospital

Alessandra Hofstadler Deiques Fleig, Isabella Brixner, Natalia Colissi, Alessandra Boesing, Andressa Seehaber, Luiz Fiori, Bruna Santos, Alexandra Cardoso, Alessandro Anversa, Matheus Donadel, Stefano Aita, Marcelo Silva, Clandio Marques, Jacqueline Vaz, Marcia Schmidt, Carlos Gottschall, Alexandre Quadros, Mateus Marques, Anibal Abelin
European Respiratory Journal 2020 56: 3062; DOI: 10.1183/13993003.congress-2020.3062
Alessandra Hofstadler Deiques Fleig
1Federal University of Santa Maria, Santa Maria, Brazil
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  • For correspondence: alefleig@yahoo.com.br
Isabella Brixner
1Federal University of Santa Maria, Santa Maria, Brazil
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Natalia Colissi
1Federal University of Santa Maria, Santa Maria, Brazil
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Alessandra Boesing
1Federal University of Santa Maria, Santa Maria, Brazil
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Andressa Seehaber
1Federal University of Santa Maria, Santa Maria, Brazil
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Luiz Fiori
1Federal University of Santa Maria, Santa Maria, Brazil
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Bruna Santos
1Federal University of Santa Maria, Santa Maria, Brazil
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Alexandra Cardoso
1Federal University of Santa Maria, Santa Maria, Brazil
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Alessandro Anversa
1Federal University of Santa Maria, Santa Maria, Brazil
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Matheus Donadel
1Federal University of Santa Maria, Santa Maria, Brazil
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Stefano Aita
1Federal University of Santa Maria, Santa Maria, Brazil
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Marcelo Silva
1Federal University of Santa Maria, Santa Maria, Brazil
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Clandio Marques
2Franciscan University, Santa Maria, Brazil
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Jacqueline Vaz
3Institute of Cardiology of Rio Grande do Sul, Porto Alegre, Brazil
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Marcia Schmidt
3Institute of Cardiology of Rio Grande do Sul, Porto Alegre, Brazil
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Carlos Gottschall
3Institute of Cardiology of Rio Grande do Sul, Porto Alegre, Brazil
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Alexandre Quadros
3Institute of Cardiology of Rio Grande do Sul, Porto Alegre, Brazil
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Mateus Marques
1Federal University of Santa Maria, Santa Maria, Brazil
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Anibal Abelin
1Federal University of Santa Maria, Santa Maria, Brazil
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Abstract

Background: Prior studies have found that smokers with ST-segment elevation myocardial infarction (STEMI) are younger, have fewer coexisting high-features and lower mortality than nonsmokers.

Objectives: To evaluate the relationship between cigarette smoking status and in-hospital outcomes of patients treated with STEMI at a tertiary hospital.

Methods: Prospective cohort study of a single center. Patients admitted with STEMI between September 2016 and September 2019 were included. Smoking status was categorized as never-smokers, current smokers and former smokers. Clinical characteristics, length of stay, all-cause mortality and major cardiovascular events (MACE, defined as the composite of total mortality, re-infarction, stroke and cardiac arrest) during the in-hospital period were evaluated. Chi-square test, ANOVA and Tukey test, and the Kruskal-Wallis H test were used, as appropriate. P<.05 was considered statistically significant.

Results: Of the 230 patients hospitalized with STEMI in the period, 92 (40%) were currently smoking and 63 (27.3%) were former smokers. Current smokers (57.2±11.4 years) were younger than never-smokers (63.7±11.4 years) (p = 0.001) and former smokers (64.8±9.6 years) (p<0.001). Baseline characteristics and use of reperfusion therapy were unrelated to smoking status. Never-smokers, current smokers and former smokers had similar median length of stay, in-hospital mortality (6.8% vs. 9.9% vs. 11.3%, respectively, p=0.65) and MACE (p=0.41).

Conclusion: Compared to never-smokers and former smokers, current smoking is associated with the occurrence of STEMI at a younger age and with similar in-hospital mortality.

  • Smoking
  • Extrapulmonary impact
  • Behavioral science

Footnotes

Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3062.

This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2020
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Smoking status and in-hospital outcomes of ST elevation myocardial infarction patients in a Brazilian public university hospital
Alessandra Hofstadler Deiques Fleig, Isabella Brixner, Natalia Colissi, Alessandra Boesing, Andressa Seehaber, Luiz Fiori, Bruna Santos, Alexandra Cardoso, Alessandro Anversa, Matheus Donadel, Stefano Aita, Marcelo Silva, Clandio Marques, Jacqueline Vaz, Marcia Schmidt, Carlos Gottschall, Alexandre Quadros, Mateus Marques, Anibal Abelin
European Respiratory Journal Sep 2020, 56 (suppl 64) 3062; DOI: 10.1183/13993003.congress-2020.3062

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Smoking status and in-hospital outcomes of ST elevation myocardial infarction patients in a Brazilian public university hospital
Alessandra Hofstadler Deiques Fleig, Isabella Brixner, Natalia Colissi, Alessandra Boesing, Andressa Seehaber, Luiz Fiori, Bruna Santos, Alexandra Cardoso, Alessandro Anversa, Matheus Donadel, Stefano Aita, Marcelo Silva, Clandio Marques, Jacqueline Vaz, Marcia Schmidt, Carlos Gottschall, Alexandre Quadros, Mateus Marques, Anibal Abelin
European Respiratory Journal Sep 2020, 56 (suppl 64) 3062; DOI: 10.1183/13993003.congress-2020.3062
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