Abstract
Introduction: Sarcoidosis is a multisystem inflammatory disease of unknown etiology, which is characterised by granuloma formation. Clinical presentation, organ involvement, disease severity and prognosis vary significantly according to region and population.
Aim: The aim of these study is to assess epidemiological and clinical characteristics, staginf factors and clinical course of the disease in Greek patients with Sarcoidosis.
Methods: Data were collected and analysed retrospectively, between January 2002 and December 2019 from the Sarcoidosis Center of General Hospital of Chest Diseases in Athens. Demographics, stage at diagnosis, extra- pulmonary manifestations, comorbidities, symptoms, pulmonary function testing and current treatments were recorded.
Results: A total of 550 cases with pathologicaly confirmed sarcoidosis were analysed. The mean age at diagnosis was 46 years (25 to 79 years), 58% were females and 42% were males. Lung involvement (89%) was the most common manifestation, 48% of the patients had extra pulmonary manifestations. At the time of diagnosis most patients were in radiological stage II (43%) and I (41%). The most prevalent CT findings were lymph node enlargement, nodules, traction bronchiectasis and groud glass opacities. The most common presenting symptoms were dry cough, dyspnoea with exertion, fatigue, chest discomfort and arthralgia. Systemic treatment was administered in 46.7% of cases.
Coclusion: The epidimiological and clinical characteristics of this cohort of Greek patients with Sarcoidosis were similar to those described in other Western Europe populations and the US ACCESS study, however the mean age at diagnosis seems to be higher in Greece.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3006.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020