Abstract
Introduction and Aim: Sarcoidosis is widely considered to be a disease with dominant Th1 response. However, results of several recent studies suggested similar prevalence of Th2-dominant allergic diseases in patients with sarcoidosis and general population. The aim of our study was to assess the occurrence of atopic disorders in patients with sarcoidosis and compare it with local population.
Material and Methods: We created a questionnaire focusing on sarcoidosis and allergy and surveyed all adults treated for sarcoidosis in our tertiary pulmonary clinic. We combined the results with our medical records to create a comprehensive database for statistical analysis. We compared the results with previously published local data of the ECAP study (Epidemiology of the Allergic Diseases in Poland).
Results: Among 329 adults who answered the survey, 114 (34%) reported at least 1 allergic disease. Asthma, atopic dermatitis and food allergy rates were similar to those of local population reported in epidemiological data (11,9% vs 9%, 2,7% vs 4% and 4,9% vs 5,0%, respectively). Urticaria was more frequent in sarcoidosis patients (15,5% vs 8%) and allergic rhinitis was nearly 3 times less common (11,5 vs 30%). Interestingly, within surveyed group, asthmatics reported more severe sarcoidosis symptoms and all patients with atopic diseases were more likely to report seasonal fluctuations in their perception of sarcoidosis symptoms, compared to those with no allergic disorders (23% vs 7%, respectively, p<0,001).
Conclusions: Prevalence of allergy among sarcoidosis patients is lower than in general population, but patients with allergic diseases tend be more symptomatic and perceive their sarcoidosis as more severe.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3004.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020