Abstract
Aim: Respiratory and musculoskeletal involvement are seen in individuals with cystic fibrosis (CF). This study aimed to compare respiratory muscle endurance, peripheral muscle strength, and walking speed in adult CF patients and healthy controls.
Methods: Twenty-three patients with adult CF (23.61±3.07 years, 10 F, 13 M) and 23 healthy individuals (22.26±3.02 yrs, 10 F, 13 M) participated. Respiratory muscle endurance was measured at 60% of maximal inspiratory pressure at a constant threshold load, and the duration was recorded. Quadriceps muscle strength was evaluated using a dynamometer. Gait parameters were assessed using the Biodex Gait Trainer. Step cycle (s), walking speed (m/s), the number of steps per minute, and ambulation index were measured for six minutes.
Results: Respiratory muscle endurance and quadriceps muscle strength of adult CF patients were lower than those of healthy controls (p<0.05). Walking speed (0.9±0.3 m/s vs 1.0±0.2 m/s) was significantly lower in CF patients than healthy individuals (p<0.05). Step cycle (0.8±0.1 s vs. 0.9±0.1 s), number of steps (567.3± 124.1 vs. 587.8±103.8), and ambulation index (89.1±4.9 vs. 91.4±4.3) were similar between CF patients and healthy individuals (p>0.05).
Method: Respiratory muscle endurance, peripheral muscle strength, and walking speed are adversely affected in adult patients with CF. Gait parameters as well as peripheral muscle strength, and respiratory muscle endurance should be considered when planning a pulmonary rehabilitation program in adult CF patients.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 2969.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020