Abstract
Lymphangioleiomyomatosis (LAM) is a rare (1/million inhabitants) systemic disorder that mainly affects women and results in cystic lung destruction. Physical activity levels (PAL) is an important clinical outcome in subjects with chronic respiratory diseases; however, there is no previous study reporting PAL in subjects with LAM.
Objectives: to evaluate the PAL in women with LAM.
Methods: Thirty-eight women with LAM diagnosis were included. PAL was evaluated using accelerometer (Actigraph, GT3X) for one week and the variables sedentarism, number of steps, and moderate-to-vigorous physical activity (MVPA). Lung function, health-related quality of life (CRQ), anxiety and depression status (HADS) and 6-minute walking test (6MWT) were also evaluated. The Kolmogorov-Smirnov test assessed data normality. Pearson correlation was used to evaluate the association between PAL and physical capacity and lung function.
Results: Women were 46.6±10.7 yrs-old and with mean lung function FEV1 75±19.7%. They walked 6,644±3,944 steps per day and spent most of the time in sedentary behavior (72±12%) and low time in moderate-to-severe activity (2.4±3.2%). Physical capacity was 95.1±17.8% of the predict in the 6MWT. HADS scored 7.0± 4.4 and 5.1 ± 3.8 and 10 and 6 women presented anxiety and depression symptoms, respectively. Quality of life by CRQ presented 63.58±13.41escore (dimension of dyspnea scored the worst). There was no association between PAL and physical capacity or lung function.
Conclusion: Women with LAM present a decreased PAL despite having a good physical capacity and quality of life.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 257.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020