Abstract
Introduction: The presence of chronic bronchitis (CB) symptoms is associated with increased risk of cardiovascular (CV) disease, especially in those with chronic lung disease. Here, we assessed aortic pulse wave velocity (PWV), a measure of CV risk, in young smokers classified as chronic bronchitic or not.
Methods: All participants from the BLF Early COPD Cohort (30-45 years old, current smokers with > 10 pack years smoking and without confirmed COPD at baseline) who underwent aortic PWV (Vicorder, UK) were included. Age, gender, body mass index (BMI), heart rate (HR), blood pressure (BP), post-bronchodilator spirometry (FEV1 %pred) and mean arterial pressure (MAP) were also recorded. Participants were classified as CB or not according to “Do you usually have a productive cough on most days for at least 3 months a year for 2 consecutive years”.
Results: Of the 157 subjects, aortic PWV was not different between those classified as chronic bronchitic (n=46) or not (n=111), p=0.634. As expected, male gender, age and MAP were all associated with increased aortic PWV, p<0.01.
Conclusions: Young smokers classified as chronic bronchitic did not have greater aortic stiffness compared to those who were not at the baseline study of the BLF Early COPD cohort.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1883.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020