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King’s Brief Interstitial Lung Disease (K-BILD) questionnaire: content relevance in progressive fibrosing ILD (PF-ILD)

Surinder S. Birring, Donald M. Bushnell, Katelyn Cutts, Michael Baldwin, Klaus B. Rohr, Natalia Male
European Respiratory Journal 2020 56: 1813; DOI: 10.1183/13993003.congress-2020.1813
Surinder S. Birring
1King's College Hospital NHS Foundation Trust, London, United Kingdom
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  • For correspondence: surinder.birring@nhs.net
Donald M. Bushnell
2Evidera, Bethesda, MD, United States of America
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Katelyn Cutts
2Evidera, Bethesda, MD, United States of America
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Michael Baldwin
3Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany
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Klaus B. Rohr
3Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany
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Natalia Male
3Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany
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Abstract

Background: Further validation of K-BILD questionnaire content is needed in PF-ILD.

Aim: Assess relevance and comprehension of K-BILD questionnaire content in PF-ILD.

Methods: 20 adult ILD patients (US [n=15]; Germany [n=5]) with prespecified PF-ILD criteria (eg, ≥10% relative decline in FVC%pred) were interviewed. After concept elicitation, participants completed the 15-item K-BILD questionnaire assessing 3 domains (breathlessness/activities, psychological and chest symptoms) within the past 2 weeks, followed by an interview. Interviews were audio-recorded, transcribed and coded for qualitative content analysis using ATLAS.ti.

Results: Reporting values as median (range), participants were aged 73 (48–81) years with 67% (47–95) FVC%pred. Rheumatoid arthritis-associated (25%), hypersensitivity pneumonitis (20%) and other fibrosing (30%) ILD were amongst the underlying ILD diagnoses for this cohort. Breathlessness was one of the most frequent and impactful K-BILD items reported by patients. Comprehension of K-BILD time period was high, with most participants stating they were thinking of the past 2 weeks (n=14/20, 70%) and 100% (n=19/19) reporting ability to recall 2 weeks’ time. K-BILD items were well understood by participants, capturing relevant aspects of PF-ILD affecting most participants (Figure).

Conclusion: For patients with PF-ILD, K-BILD is well understood and contains relevant concepts.

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Footnotes

Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1813.

This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2020
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King’s Brief Interstitial Lung Disease (K-BILD) questionnaire: content relevance in progressive fibrosing ILD (PF-ILD)
Surinder S. Birring, Donald M. Bushnell, Katelyn Cutts, Michael Baldwin, Klaus B. Rohr, Natalia Male
European Respiratory Journal Sep 2020, 56 (suppl 64) 1813; DOI: 10.1183/13993003.congress-2020.1813

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King’s Brief Interstitial Lung Disease (K-BILD) questionnaire: content relevance in progressive fibrosing ILD (PF-ILD)
Surinder S. Birring, Donald M. Bushnell, Katelyn Cutts, Michael Baldwin, Klaus B. Rohr, Natalia Male
European Respiratory Journal Sep 2020, 56 (suppl 64) 1813; DOI: 10.1183/13993003.congress-2020.1813
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