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Dose optimisation of first-line tuberculosis drugs using therapeutic drug monitoring in saliva: feasible for rifampicin, not for isoniazid

Simone H.J. van den Elsen, Onno W. Akkerman, Mireille Wessels, Erwin M. Jongedijk, Samiksha Ghimire, Tjip S. van der Werf, Mathieu S. Bolhuis, Daan J. Touw, Jan-Willem C. Alffenaar
European Respiratory Journal 2020 56: 2000803; DOI: 10.1183/13993003.00803-2020
Simone H.J. van den Elsen
1University of Groningen, University Medical Center Groningen, Dept of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands
2Hospital Group Twente, Dept of Clinical Pharmacy, Almelo and Hengelo, The Netherlands
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Onno W. Akkerman
3University of Groningen, University Medical Center Groningen, Tuberculosis Center Beatrixoord, Haren, The Netherlands
4University of Groningen, University Medical Center Groningen, Dept of Pulmonary Diseases and Tuberculosis, Groningen, The Netherlands
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Mireille Wessels
1University of Groningen, University Medical Center Groningen, Dept of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands
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Erwin M. Jongedijk
1University of Groningen, University Medical Center Groningen, Dept of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands
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Samiksha Ghimire
1University of Groningen, University Medical Center Groningen, Dept of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands
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Tjip S. van der Werf
4University of Groningen, University Medical Center Groningen, Dept of Pulmonary Diseases and Tuberculosis, Groningen, The Netherlands
5University of Groningen, University Medical Center Groningen, Dept of Internal Medicine, Groningen, The Netherlands
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Mathieu S. Bolhuis
1University of Groningen, University Medical Center Groningen, Dept of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands
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Daan J. Touw
1University of Groningen, University Medical Center Groningen, Dept of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands
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Jan-Willem C. Alffenaar
1University of Groningen, University Medical Center Groningen, Dept of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands
6Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia
7Westmead Hospital, Sydney, Australia
8Marie Bashir Institute of Infectious Diseases and Biosecurity, Sydney, Australia
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Vol 56 Issue 4 Table of Contents
European Respiratory Journal: 56 (4)
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Dose optimisation of first-line tuberculosis drugs using therapeutic drug monitoring in saliva: feasible for rifampicin, not for isoniazid
Simone H.J. van den Elsen, Onno W. Akkerman, Mireille Wessels, Erwin M. Jongedijk, Samiksha Ghimire, Tjip S. van der Werf, Mathieu S. Bolhuis, Daan J. Touw, Jan-Willem C. Alffenaar
European Respiratory Journal Oct 2020, 56 (4) 2000803; DOI: 10.1183/13993003.00803-2020

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Dose optimisation of first-line tuberculosis drugs using therapeutic drug monitoring in saliva: feasible for rifampicin, not for isoniazid
Simone H.J. van den Elsen, Onno W. Akkerman, Mireille Wessels, Erwin M. Jongedijk, Samiksha Ghimire, Tjip S. van der Werf, Mathieu S. Bolhuis, Daan J. Touw, Jan-Willem C. Alffenaar
European Respiratory Journal Oct 2020, 56 (4) 2000803; DOI: 10.1183/13993003.00803-2020
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