Figures
- FIGURE 1
Summary of differences in the predicted values using the original Global Lung Function Initiative (GLI) equations (red) and the updated equations (blue).
Tables
- TABLE 2
The corrected equations for predicted values for the median (M), the variability around the median (S) and the skewness (L) for each of the TLCO test outcomes (transfer factor of the lung for carbon monoxide (TLCO), transfer coefficient of the lung for carbon monoxide (KCO) and alveolar volume (VA))
M S L Male TLCO mmol·min-1·kPa-1 exp(-8.129189 + 2.018368·ln(height) - 0.012425·ln(age) + Mspline) exp(-1.98996 + 0.03536·ln (age) + Sspline) 0.39482 DLCO mL·min-1·mmHg-1 exp(-7.034920 + 2.018368·ln(height) - 0.012425·ln(age) + Mspline) KCO (SI) mmol·min-1·kPa-1·L-1 exp(2.994137 - 0.415334·ln(height) - 0.113166·ln(age) + Mspline) exp(-1.98186 + 0.01460·ln(age) + Sspline) 0.67330 KCO (trad) mL·min-1·mmHg-1·L-1 exp(4.088408 - 0.415334·ln(height) - 0.113166·ln(age) + Mspline) VA L exp(-11.086573 + 2.430021·ln(height) + 0.097047·ln(age) + Mspline) exp(-2.20953 + 0.01937·ln(age) + Sspline) 0.62559 Female TLCO mmol·min-1·kPa-1 exp(-6.253720 + 1.618697·ln(height) - 0.015390·ln(age) + Mspline) exp(-1.82905 - 0.01815·ln(age) + Sspline) 0.24160 DLCO mL·min-1·mmHg-1 exp(-5.159451 + 1.618697·ln(height) - 0.015390·ln(age) + Mspline) KCO (SI) mmol·min-1·kPa-1·L-1 exp(4.037222 - 0.645656·ln(height) - 0.097395·ln(age) + Mspline) exp(-1.63787 - 0.07757·ln(age) + Sspline) 0.48963 KCO (trad) mL·min-1·mmHg-1·L-1 exp(5.131492 - 0.645656·ln(height) - 0.097395·ln(age) + Mspline) VA L exp(-9.873970 + 2.182316·ln(height) + 0.082868·ln(age) + Mspline) exp(-2.08839 - 0.01334·ln(age) + Sspline) 0.51919 Mspline, Sspline correspond to the age-varying coefficients from the look-up tables provided in the supplementary material. Height and age are expressed as cm and years, respectively. Predicted value: M; lower limit of normal (5th percentile): exp(ln(M) + ln(1 - 1.645·L·S)/L); upper limit of normal (5th percentile): exp(ln(M) + ln(1 + 1.645·L·S)/L); z-score: ((measured/M)L - 1)/(L·S); % predicted: (measured/M)·100; exp: natural exponential; ln: natural logarithm. This table has been amended in the article originally published in the September 2017 issue of the European Respiratory Journal.
