European Respiratory Journal: 56 (3)

01 September 2020; volume 56, issue 3

Editorials

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Celebrating the ERS HERMES Self-Assessment Course
Robert Primhak, Zuzana Tumova, Amy Auer, Daiana Stolz

European Respiratory Journal 56 (3) 2002895; DOI: 10.1183/13993003.02895-2020 Published 3 September 2020
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ERS Scientific Working Group 09.04, “Psychologists and behavioural scientists”: the next step towards multidisciplinary respiratory care
Andreas von Leupoldt, Lisa Jane Brighton, Jeannette Peters, Eleonora Volpato, Marieke Verkleij, Ann Hutchinson, Monique Heijmans, Ingeborg Farver-Vestergaard, Daniel Langer, Martijn A. Spruit on behalf of the ERS Scientific Working Group 09.04

European Respiratory Journal 56 (3) 2001881; DOI: 10.1183/13993003.01881-2020 Published 17 September 2020
Open Access
Pandemic treatments on trial: the bigger picture. N of many thinking in an N of one scenario
Tom Kotsimbos, Marc Humbert

European Respiratory Journal 56 (3) 2002281; DOI: 10.1183/13993003.02281-2020 Published 17 September 2020
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Imaging risk in pulmonary arterial hypertension
Roberto Badagliacca, Carmine Dario Vizza

European Respiratory Journal 56 (3) 2002313; DOI: 10.1183/13993003.02313-2020 Published 24 September 2020
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Carriers of a single CFTR mutation are asymptomatic: an evolving dogma?
Clémence Martin, Pierre-Régis Burgel

European Respiratory Journal 56 (3) 2002645; DOI: 10.1183/13993003.02645-2020 Published 10 September 2020
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Intermittent regimens for tuberculosis treatment: Back to the Future?
Jan-Willem C. Alffenaar, Simon Tiberi, Daniela M. Cirillo, Giovanni Battista Migliori

European Respiratory Journal 56 (3) 2002510; DOI: 10.1183/13993003.02510-2020 Published 3 September 2020
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Sarcoidosis in a time of pandemic
Praveen Govender, Yvette C. Cozier

European Respiratory Journal 56 (3) 2002376; DOI: 10.1183/13993003.02376-2020 Published 3 September 2020
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ECMO support for viral induced cardiogenic shock: a bridge too far?
Trevor J. Williams, Vincent Pellegrino

European Respiratory Journal 56 (3) 2002129; DOI: 10.1183/13993003.02129-2020 Published 3 September 2020
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Oscillometry: old physiology with a bright future
Peter M.A. Calverley, Ramon Farré

European Respiratory Journal 56 (3) 2001815; DOI: 10.1183/13993003.01815-2020 Published 10 September 2020

Task Force Report

Open Access
COVID-19: guidance on palliative care from a European Respiratory Society international task force
Daisy J.A. Janssen, Magnus Ekström, David C. Currow, Miriam J. Johnson, Matthew Maddocks, Anita K. Simonds, Thomy Tonia, Kristoffer Marsaa

European Respiratory Journal 56 (3) 2002583; DOI: 10.1183/13993003.02583-2020 Published 3 September 2020

Original Articles

Pulmonary hypertension
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  A comprehensive echocardiographic method for risk stratification in pulmonary arterial hypertension
  Stefano Ghio, Valentina Mercurio, Federico Fortuni, Paul R. Forfia, Henning Gall, Ardeschir Ghofrani, Stephen C. Mathai, Jeremy A. Mazurek, Monica Mukherjee, Manuel Richter, Laura Scelsi, Paul M. Hassoun, Khodr Tello TAPSE in PAH investigators
  
  European Respiratory Journal 56 (3) 2000513; DOI: 10.1183/13993003.00513-2020 Published 24 September 2020
Lung structure and function
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  Normal spirometry predictive values for the Western Indian adult population
  Dhiraj Agarwal, Richard A. Parker, Hilary Pinnock, Sudipto Roy, Deesha Ghorpade, Sundeep Salvi, Parag Khatavkar, Sanjay Juvekar for the RESPIRE collaboration
  
  European Respiratory Journal 56 (3) 1902129; DOI: 10.1183/13993003.02129-2019 Published 17 September 2020
Cystic fibrosis
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  Morbidity and mortality in carriers of the cystic fibrosis mutation CFTR Phe508del in the general population
  Yunus Çolak, Børge G. Nordestgaard, Shoaib Afzal
  
  European Respiratory Journal 56 (3) 2000558; DOI: 10.1183/13993003.00558-2020 Published 10 September 2020
Infectious disease
- Open Access
  Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue
  Jennifer A. Aguiar, Benjamin J-M. Tremblay, Michael J. Mansfield, Owen Woody, Briallen Lobb, Arinjay Banerjee, Abiram Chandiramohan, Nicholas Tiessen, Quynh Cao, Anna Dvorkin-Gheva, Spencer Revill, Matthew S. Miller, Christopher Carlsten, Louise Organ, Chitra Joseph, Alison John, Paul Hanson, Richard C. Austin, Bruce M. McManus, Gisli Jenkins, Karen Mossman, Kjetil Ask, Andrew C. Doxey, Jeremy A. Hirota
  
  European Respiratory Journal 56 (3) 2001123; DOI: 10.1183/13993003.01123-2020 Published 3 September 2020
Tuberculosis
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  The risk of multidrug- or rifampicin-resistance in males versus females with tuberculosis
  C. Finn McQuaid, Katherine C. Horton, Anna S. Dean, Gwenan M. Knight, Richard G. White
  
  European Respiratory Journal 56 (3) 2000626; DOI: 10.1183/13993003.00626-2020 Published 17 September 2020
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  Fully weekly antituberculosis regimen: a proof-of-concept study
  Fatma Kort, Laure Fournier Le Ray, Aurélie Chauffour, Vincent Jarlier, Nacer Lounis, Koen Andries, Alexandra Aubry, Lorenzo Guglielmetti, Nicolas Veziris
  
  European Respiratory Journal 56 (3) 1902502; DOI: 10.1183/13993003.02502-2019 Published 3 September 2020
Sarcoidosis
- Open Access
  Risk of first and recurrent serious infection in sarcoidosis: a Swedish register-based cohort study
  Marios Rossides, Susanna Kullberg, Anders Eklund, Daniela Di Giuseppe, Johan Grunewald, Johan Askling, Elizabeth V. Arkema
  
  European Respiratory Journal 56 (3) 2000767; DOI: 10.1183/13993003.00767-2020 Published 3 September 2020
Critical care
- Open Access
  Mechanical circulatory support in refractory cardiogenic shock due to influenza virus-related myocarditis
  Jan-Thorben Sieweke, Muharrem Akin, Sebastian Stetskamp, Christian Riehle, Danny Jonigk, Ulrike Flierl, Tobias J. Pfeffer, Valentin Hirsch, Jochen Dutzmann, Marius M. Hoeper, Christian Kühn, Johann Bauersachs, Andreas Schäfer
  
  European Respiratory Journal 56 (3) 2000925; DOI: 10.1183/13993003.00925-2020 Published 3 September 2020
COPD
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  Day-to-day variability of forced oscillatory mechanics for early detection of acute exacerbations in COPD
  Sabine C. Zimmermann, Jacqueline Huvanandana, Chinh D. Nguyen, Amy Bertolin, Joanna C. Watts, Alessandro Gobbi, Claude S. Farah, Matthew J. Peters, Raffaele L. Dellacà, Gregory G. King, Cindy Thamrin
  
  European Respiratory Journal 56 (3) 1901739; DOI: 10.1183/13993003.01739-2019 Published 10 September 2020
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  Autotitrating external positive end-expiratory airway pressure to abolish expiratory flow limitation during tidal breathing in patients with severe COPD: a physiological study
  Eui-Sik Suh, Pasquale Pompilio, Swapna Mandal, Peter Hill, Georgios Kaltsakas, Patrick B. Murphy, Robert Romano, John Moxham, Raffaele Dellaca, Nicholas Hart
  
  European Respiratory Journal 56 (3) 1902234; DOI: 10.1183/13993003.02234-2019 Published 10 September 2020
COPD and rehabilitation
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  Effects of downhill walking in pulmonary rehabilitation for patients with COPD: a randomised controlled trial
  Carlos Augusto Camillo, Christian Robert Osadnik, Chris Burtin, Stephanie Everaerts, Miek Hornikx, Heleen Demeyer, Matthias Loeckx, Fernanda Machado Rodrigues, Karen Maes, Ghislaine Gayan-Ramirez, Wim Janssens, Thierry Troosters
  
  European Respiratory Journal 56 (3) 2000639; DOI: 10.1183/13993003.00639-2020 Published 17 September 2020
COPD and basic science
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  Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice
  Jie-Sen Zhou, Zhou-Yang Li, Xu-Chen Xu, Yun Zhao, Yong Wang, Hai-Pin Chen, Min Zhang, Yin-Fang Wu, Tian-Wen Lai, Chun-Hong Di, Ling-Ling Dong, Juan Liu, Nan-Xia Xuan, Chen Zhu, Yan-Ping Wu, Hua-Qiong Huang, Fu-Gui Yan, Wen Hua, Yi Wang, Wei-Ning Xiong, Hui Qiu, Tao Chen, Dong Weng, Hui-Ping Li, Xiaobo Zhou, Lie Wang, Fang Liu, Xin Lin, Song-Min Ying, Wen Li, Mitsuru Imamura, Mary E. Choi, Martin R. Stampfli, Augustine M.K. Choi, Zhi-Hua Chen, Hua-Hao Shen
  
  European Respiratory Journal 56 (3) 2000404; DOI: 10.1183/13993003.00404-2020 Published 3 September 2020
Asthma
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  SMART and as-needed therapies in mild-to-severe asthma: a network meta-analysis
  Paola Rogliani, Beatrice Ludovica Ritondo, Josuel Ora, Mario Cazzola, Luigino Calzetta
  
  European Respiratory Journal 56 (3) 2000625; DOI: 10.1183/13993003.00625-2020 Published 10 September 2020
- Open Access
  Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study
  Thanh T. Hoang, Sinjini Sikdar, Cheng-Jian Xu, Mi Kyeong Lee, Jonathan Cardwell, Erick Forno, Medea Imboden, Ayoung Jeong, Anne-Marie Madore, Cancan Qi, Tianyuan Wang, Brian D. Bennett, James M. Ward, Christine G. Parks, Laura E. Beane-Freeman, Debra King, Alison Motsinger-Reif, David M. Umbach, Annah B. Wyss, David A. Schwartz, Juan C. Celedón, Catherine Laprise, Carole Ober, Nicole Probst-Hensch, Ivana V. Yang, Gerard H. Koppelman, Stephanie J. London
  
  European Respiratory Journal 56 (3) 2000217; DOI: 10.1183/13993003.00217-2020 Published 3 September 2020
Asthma and basic science
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  Innate lymphoid cells in isocyanate-induced asthma: role of microRNA-155
  Evy E. Blomme, Sharen Provoost, Erica Bazzan, Hannelore P. Van Eeckhoutte, Mirjam P. Roffel, Lore Pollaris, Annelies Bontinck, Matteo Bonato, Louise Vandenbroucke, Fien Verhamme, Guy F. Joos, Manuel G. Cosio, Jeroen A. J. Vanoirbeek, Guy G. Brusselle, Marina Saetta, Tania Maes
  
  European Respiratory Journal 56 (3) 1901289; DOI: 10.1183/13993003.01289-2019 Published 24 September 2020
Lung transplantation
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  Late-onset “acute fibrinous and organising pneumonia” impairs long-term lung allograft function and survival
  Arno Vanstapel, Stijn E. Verleden, Birgit Weynand, Eric Verbeken, Laurens De Sadeleer, Bart M. Vanaudenaerde, Geert M. Verleden, Robin Vos the Leuven Lung Transplant Group
  
  European Respiratory Journal 56 (3) 1902292; DOI: 10.1183/13993003.02292-2019 Published 3 September 2020

Review

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Artificial intelligence techniques in asthma: a systematic review and critical appraisal of the existing literature
Konstantinos P. Exarchos, Maria Beltsiou, Chainti-Antonella Votti, Konstantinos Kostikas

European Respiratory Journal 56 (3) 2000521; DOI: 10.1183/13993003.00521-2020 Published 3 September 2020

Back to Basics

Open Access
Pathogenesis of COVID-19-induced ARDS: implications for an ageing population
Manuel A. Torres Acosta, Benjamin D. Singer

European Respiratory Journal 56 (3) 2002049; DOI: 10.1183/13993003.02049-2020 Published 24 September 2020

Agora

Research letters
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  Extrafine triple therapy in patients with asthma and persistent airflow limitation
  Dave Singh, Johann Christian Virchow, Giorgio Walter Canonica, Andrea Vele, Maxim Kots, George Georges, Alberto Papi
  
  European Respiratory Journal 56 (3) 2000476; DOI: 10.1183/13993003.00476-2020 Published 24 September 2020
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  Effect of history of tuberculosis on specificity of Xpert MTB/RIF
  Frederick Haraka, Samuel G. Schumacher, Amanda Ross, Anna Mantsoki, Sebastien Gagneux, Klaus Reither, Claudia M. Denkinger
  
  European Respiratory Journal 56 (3) 2000343; DOI: 10.1183/13993003.00343-2020 Published 24 September 2020
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  Effect of long-acting β-agonist on bronchodilator response in children with asthma
  Jessica Taytard, Camille Aupiais, Sophie Jovien, Jessica Assouline Kabla, Noémie Haziot, Marilyn Fuger, Corinne Alberti, Nicole Beydon
  
  European Respiratory Journal 56 (3) 1902010; DOI: 10.1183/13993003.02010-2019 Published 24 September 2020
- Open Access
  Elevated ACE-2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-CoV-2 entry and replication
  Mengfei Chen, Wenjuan Shen, Nicholas R. Rowan, Heather Kulaga, Alexander Hillel, Murugappan Ramanathan Jr, Andrew P. Lane
  
  European Respiratory Journal 56 (3) 2001948; DOI: 10.1183/13993003.01948-2020 Published 24 September 2020
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  Ventilatory demand–capacity imbalance during incremental exercise in COPD: an in silico perspective
  J. Alberto Neder
  
  European Respiratory Journal 56 (3) 2000495; DOI: 10.1183/13993003.00495-2020 Published 17 September 2020
- Open Access
  Iron bioavailability and cardiopulmonary function during ascent to very high altitude
  David A. Holdsworth, Matthew C. Frise, Josh Bakker-Dyos, Christopher Boos, Keith L. Dorrington, David Woods, Adrian Mellor, Peter A. Robbins
  
  European Respiratory Journal 56 (3) 1902285; DOI: 10.1183/13993003.02285-2019 Published 17 September 2020
- Open Access
  Socioeconomic correlates of SARS-CoV-2 and influenza H1N1 outbreaks
  Jan Christian Kaiser, Georgios T. Stathopoulos
  
  European Respiratory Journal 56 (3) 2001400; DOI: 10.1183/13993003.01400-2020 Published 17 September 2020
- Open Access
  Comparison of severity scores for COVID-19 patients with pneumonia: a retrospective study
  Guohui Fan, Chao Tu, Fei Zhou, Zhibo Liu, Yeming Wang, Bin Song, Xiaoying Gu, Yimin Wang, Yuan Wei, Hui Li, Xudong Wu, Jiuyang Xu, Shengjin Tu, Yi Zhang, Wenjuan Wu, Bin Cao
  
  European Respiratory Journal 56 (3) 2002113; DOI: 10.1183/13993003.02113-2020 Published 10 September 2020
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  Circulating RNA differences between patients with stable and progressive idiopathic pulmonary fibrosis
  Britt Clynick, Helen E. Jo, Tamera J. Corte, Ian N. Glaspole, Christopher Grainge, Peter M.A. Hopkins, Paul N. Reynolds, Sally Chapman, E. Haydn Walters, Christopher Zappala, Gregory J. Keir, Wendy A. Cooper, Annabelle M. Mahar, Samantha Ellis, Nicole S. Goh, Svetlana Baltic, Marisa Ryan, Dino B.A. Tan, Yuben P. Moodley
  
  European Respiratory Journal 56 (3) 1902058; DOI: 10.1183/13993003.02058-2019 Published 10 September 2020
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  The impact of different antibiotic treatment regimens on mortality in Mycobacterium avium complex pulmonary disease: a population-based cohort study
  Sarah K. Brode, Hannah Chung, Michael A. Campitelli, Jeffrey C. Kwong, Rinku Sutradhar, Alex Marchand-Austin, Kevin L. Winthrop, Frances B. Jamieson, Theodore K. Marras
  
  European Respiratory Journal 56 (3) 1901875; DOI: 10.1183/13993003.01875-2019 Published 10 September 2020
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  Evaluation of pulmonary hypertension by right heart catheterisation: does timing matter?
  Athiththan Yogeswaran, Manuel Jonas Richter, Natascha Sommer, Hossein Ardeschir Ghofrani, Werner Seeger, Henning Gall, Khodr Tello
  
  European Respiratory Journal 56 (3) 1901892; DOI: 10.1183/13993003.01892-2019 Published 3 September 2020
- Open Access
  Initial combination therapy of macitentan and tadalafil in pulmonary arterial hypertension
  Olivier Sitbon, Vincent Cottin, Matthieu Canuet, Pierre Clerson, Virginie Gressin, Loïc Perchenet, Laurent Bertoletti, Hélène Bouvaist, François Picard, Grégoire Prévot, Emmanuel Bergot, Gérald Simonneau
  
  European Respiratory Journal 56 (3) 2000673; DOI: 10.1183/13993003.00673-2020 Published 3 September 2020
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  Ozone exposure leads to changes in airway permeability, microbiota and metabolome: a randomised, double-blind, crossover trial
  Yue Niu, Renjie Chen, Cuiping Wang, Weidong Wang, Jing Jiang, Weidong Wu, Jing Cai, Zhuohui Zhao, Xiaohui Xu, Haidong Kan
  
  European Respiratory Journal 56 (3) 2000165; DOI: 10.1183/13993003.00165-2020 Published 3 September 2020
Correspondence
- Open Access
  JAK inhibitors in COVID-19: the need for vigilance regarding increased inherent thrombotic risk
  Puja Mehta, Coziana Ciurtin, Marie Scully, Marcel Levi, Rachel C. Chambers
  
  European Respiratory Journal 56 (3) 2001919; DOI: 10.1183/13993003.01919-2020 Published 24 September 2020
- Open Access
  Insight into the impact of the COVID-19 epidemic on tuberculosis burden in China
  Hongguang Chen, Konglai Zhang
  
  European Respiratory Journal 56 (3) 2002710; DOI: 10.1183/13993003.02710-2020 Published 24 September 2020
- Open Access
  Similarities between COVID-19 and anti-MDA5 syndrome: what can we learn for better care?
  Margherita Giannini, Mickael Ohana, Benoit Nespola, Giovanni Zanframundo, Bernard Geny, Alain Meyer
  
  European Respiratory Journal 56 (3) 2001618; DOI: 10.1183/13993003.01618-2020 Published 24 September 2020
- Open Access
  Antibiotics for paediatric community-acquired pneumonia in resource-constrained settings
  Amy Sarah Ginsburg, Keith P. Klugman
  
  European Respiratory Journal 56 (3) 2002773; DOI: 10.1183/13993003.02773-2020 Published 17 September 2020
- Open Access
  Characteristics and outcomes of health and social care workers testing positive for SARS-CoV-2 in the Tayside region of Scotland
  Moneeza K. Siddiqui, Benjamin Parcell, Sarah Allstaff, Colin Palmer, James D. Chalmers, Samira Bell
  
  European Respiratory Journal 56 (3) 2002568; DOI: 10.1183/13993003.02568-2020 Published 17 September 2020
- Open Access
  SARS-CoV-2 disrupts clinical research: the role of a rare disease-specific trial network
  Silke van Koningsbruggen-Rietschel, Fiona Dunlevy, Veerle Bulteel, Damian G. Downey, Lieven Dupont
  
  European Respiratory Journal 56 (3) 2002114; DOI: 10.1183/13993003.02114-2020 Published 17 September 2020
- Open Access
  COVID-19 prediction models should adhere to methodological and reporting standards
  Gary S. Collins, Maarten van Smeden, Richard D. Riley
  
  European Respiratory Journal 56 (3) 2002643; DOI: 10.1183/13993003.02643-2020 Published 10 September 2020
- Open Access
  Reply to “COVID-19 prediction models should adhere to methodological and reporting standards”
  Guangyao Wu, Henry C. Woodruff, Avishek Chatterjee, Philippe Lambin
  
  European Respiratory Journal 56 (3) 2002918; DOI: 10.1183/13993003.02918-2020 Published 10 September 2020
- Open Access
  Rationale and significance of patient selection in awake prone positioning for COVID-19 pneumonia
  Ching-Feng Huang, Chee Kiang Tay, Ya-Fang Zhuang, Jiaxuan Liu, Duu Wen Sewa
  
  European Respiratory Journal 56 (3) 2002173; DOI: 10.1183/13993003.02173-2020 Published 10 September 2020
- Open Access
  Rationale and significance of patient selection in awake prone positioning for COVID-19 pneumonia
  Ziqin Ng, Woo Chiao Tay, Choon Heng Benjamin Ho
  
  European Respiratory Journal 56 (3) 2002571; DOI: 10.1183/13993003.02571-2020 Published 10 September 2020
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  Systemic effects of fluticasone on blood eosinophils in bronchiectasis
  Brian Lipworth, Rory Chan, Chris RuiWen Kuo
  
  European Respiratory Journal 56 (3) 2002005; DOI: 10.1183/13993003.02005-2020 Published 3 September 2020
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  Blood eosinophils do not predict inhaled budesonide response in bronchiectasis
  Stefano Aliberti, Giovanni Sotgiu, Miguel-Angel Martinez Garcia
  
  European Respiratory Journal 56 (3) 2002210; DOI: 10.1183/13993003.02210-2020 Published 3 September 2020
- Open Access
  Potential of regulatory T-cell-based therapies in the management of severe COVID-19
  Emmanuel Stephen-Victor, Mrinmoy Das, Anupama Karnam, Bruno Pitard, Jean-François Gautier, Jagadeesh Bayry
  
  European Respiratory Journal 56 (3) 2002182; DOI: 10.1183/13993003.02182-2020 Published 3 September 2020
- Open Access
  Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2
  Hai-Jun Yang, Yan-Mei Zhang, Min Yang, Xing Huang
  
  European Respiratory Journal 56 (3) 2002439; DOI: 10.1183/13993003.02439-2020 Published 24 September 2020
- Open Access
  Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2
  Rong-Hui Du, Li-Rong Liang, Cheng-Qing Yang, Wen Wang, Tan-Ze Cao, Ming Li, Guang-Yun Guo, Juan Du, Chun-Lan Zheng, Qi Zhu, Ming Hu, Xu-Yan Li, Peng Peng, Huan-Zhong Shi
  
  European Respiratory Journal 56 (3) 2002961; DOI: 10.1183/13993003.02961-2020 Published 24 September 2020

Author correction

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“Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study.” Rong-Hui Du, Li-Rong Liang, Cheng-Qing Yang, Wen Wang, Tan-Ze Cao, Ming Li, Guang-Yun Guo, Juan Du, Chun-Lan Zheng, Qi Zhu, Ming Hu, Xu-Yan Li, Peng Peng and Huan-Zhong Shi. Eur Respir J 2020; 55: 2000524.
European Respiratory Journal 56 (3) 2050524; DOI: 10.1183/13993003.50524-2020 Published 24 September 2020

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Table of Contents

Editorials

Task Force Report

Original Articles

Pulmonary hypertension

Lung structure and function

Cystic fibrosis

Infectious disease

Tuberculosis

Sarcoidosis

Critical care

COPD

COPD and rehabilitation

COPD and basic science

Asthma

Asthma and basic science

Lung transplantation

Review

Back to Basics

Agora

Research letters

Correspondence

Author correction

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