Tables
- TABLE 1
Demographic, epidemiological and clinical characteristics of a cohort of 49 tuberculosis (TB) patients with coronavirus disease 2019 (COVID-19)
Variable Age years 48 (32–69) Male 40/49 (81.6%) Migrant status 26/49 (53.1%) Occupation Employed 14/48 (29.2%) Unemployed 15/48 (31.3%) Retired 14/48 (29.2%) Student 5/48 (10.4%) BCG vaccination 19/30 (63.3%) COPD/asthma 8/47 (17.0%) Diabetes mellitus 8/49 (16.3%) HIV infection 6/48 (12.5%) Renal failure 5/49 (10.2%) Liver disease 7/49 (14.3%) Alcohol abuse# 10/49 (20.4%) Smoking¶ 20/49 (40.8%) Drug abuse 4/47 (8.5%) TB Previous history of TB 13/46 (28.3%) Site Pulmonary TB only 36/49 (73.5%) Extrapulmonary TB only 1/49 (2.0%) Pulmonary TB/extrapulmonary TB (>1 site possible) 12/49 (24.5%) Site of extrapulmonary TB Bone 2/13 (15.4%) Lymphadenitis 2/13 (15.4%) Pleural 2/13 (15.4%) Central nervous system 1/13 (7.7%) Laryngeal 1/13 (7.7%) Gastrointestinal 1/13 (7.7%) Peritonitis+lymphadenitis+pleural+bone 1/13 (7.7%) Genitourinary+lymphadenitis 1/13 (7.7%) Central nervous system+lymphadenitis 1/13 (7.7%) Bone+joint+spondylodiscitis (T5-T11)+paravertebral abscesses 1/13 (7.7%) Radiological involvement Unilateral cavitary lesions 10/48 (20.8%) Bilateral cavitary lesions 13/48 (27.1%) Bilateral infiltrates (no cavities) 9/48 (18.8%) Unilateral infiltrates 16/48 (33.3%) Microbiology Sputum culture confirmation 22/49 (44.9%) (+8 sputum culture ongoing) NAAT confirmation 13/49 (26.5%) Sputum smear positive 9/49 (18.4%) Not available 5/49 (10.2%) Drug resistance Resistant 8/45 (17.8%) (4 MDR-TB) Sensitive 37/45 (82.2%) Treatment outcome Cured 6/49 (12.2%) Completed 1/49 (2.0%) On treatment 37/49 (75.5%) Died+ 5/49 (10.2%) Lost to follow-up 0 Failure 0 COVID-19 Symptoms Asymptomatic 5/48 (10.4%) Symptomatic 43/48 (89.6%) Imaging Typical (bilateral ground glass opacities) HRCT picture 21/44 (47.7%) Treatment outcome Resolved 18/49 (36.7%) Still on treatment 25/49 (51.0%) Died (at any date)+ 6/49 (12.3%) Data are presented as number/total number of patients for whom data are available (%) or median (interquartile range). #: ≥14 drinks per week in men or ≥7 drinks per week in women; ¶: current or ex-smoker; +: according to the criteria for cohort analysis of treatment results the number of patients who died during anti-TB treatment is five, but the total number of deaths is six, as one patient with post-TB treatment sequelae died after being cured for TB. BCG: bacillus Calmette–Guérin; NAAT: nucleic acid amplification test; MDR-TB: multidrug-resistant tuberculosis; HRCT: high-resolution computed tomography.
Supplementary Materials
Supplementary Material
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