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Why do we still cling to spirometry for assessing small airway function?

Frederik Trinkmann, Henrik Watz, Felix J.F. Herth
European Respiratory Journal 2020 56: 2001071; DOI: 10.1183/13993003.01071-2020
Frederik Trinkmann
1Pneumology and Critical Care Medicine, Thoraxklinik at University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC), Member of German Center for Lung Research (DZL), Heidelberg, Germany
2Dept of Biomedical Informatics of the Heinrich-Lanz-Center, University Medical Center Mannheim, Heidelberg University, Heidelberg, Germany
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  • ORCID record for Frederik Trinkmann
  • For correspondence: frederik.trinkmann@med.uni-heidelberg.de
Henrik Watz
3Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany
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Felix J.F. Herth
1Pneumology and Critical Care Medicine, Thoraxklinik at University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC), Member of German Center for Lung Research (DZL), Heidelberg, Germany
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Extract

With great interest we read the article by Arshad et al. [1] and the accompanying editorial [2] in the March 2020 issue of the European Respiratory Journal. We fully agree that early detection and small airway function are both of utmost importance for the management of obstructive lung disease. However, we have some methodological concerns in this context. These should be discussed as certain imitations of the important work at hand.

Abstract

Small airway function comprises heterogenous interactions between ventilation, diffusion, perfusion and inflammation that cannot be covered by spirometry https://bit.ly/2LiyQ5E

Footnotes

  • Conflict of interest: F. Trinkmann reports personal fees from Actelion, Berlin Chemie, Boehringer Ingelheim, Chiesi, Novartis, Mundipharma, TEVA, AstraZeneca, Bristol-Myers Squibb, GlaxoSmithKline and Roche, outside the submitted work.

  • Conflict of interest: H. Watz has nothing to disclose.

  • Conflict of interest: F.J.F. Herth has nothing to disclose.

  • Received April 7, 2020.
  • Accepted May 6, 2020.
  • Copyright ©ERS 2020
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Why do we still cling to spirometry for assessing small airway function?
Frederik Trinkmann, Henrik Watz, Felix J.F. Herth
European Respiratory Journal Jul 2020, 56 (1) 2001071; DOI: 10.1183/13993003.01071-2020

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Why do we still cling to spirometry for assessing small airway function?
Frederik Trinkmann, Henrik Watz, Felix J.F. Herth
European Respiratory Journal Jul 2020, 56 (1) 2001071; DOI: 10.1183/13993003.01071-2020
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