Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • For authors
    • Instructions for authors
    • Submit a manuscript
    • Author FAQs
    • Open access
    • COVID-19 submission information
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • For authors
    • Instructions for authors
    • Submit a manuscript
    • Author FAQs
    • Open access
    • COVID-19 submission information
  • Alerts
  • Podcasts
  • Subscriptions

Implementing lung health interventions in low- and middle-income countries: a FRESH AIR systematic review and meta-synthesis

Evelyn A. Brakema, Debbie Vermond, Hilary Pinnock, Christos Lionis, Bruce Kirenga, Pham Le An, Talant Sooronbaev, Niels H. Chavannes, M. J. J. Rianne van der Kleij on behalf of the FRESH AIR collaborators
European Respiratory Journal 2020 56: 2000127; DOI: 10.1183/13993003.00127-2020
Evelyn A. Brakema
1Dept of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Evelyn A. Brakema
  • For correspondence: evelynbrakema@gmail.com
Debbie Vermond
1Dept of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Debbie Vermond
Hilary Pinnock
2NIHR Global Health Research Unit on Respiratory Health (RESPIRE), Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Hilary Pinnock
Christos Lionis
3Clinic of Social and Family Medicine, School of Medicine, University of Crete, Heraklion, Greece
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Christos Lionis
Bruce Kirenga
4Dept of Medicine and Makerere Lung Institute, Makerere University, Kampala, Uganda
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Bruce Kirenga
Pham Le An
5Center of Training Family Medicine, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Pham Le An
Talant Sooronbaev
6Pulmonary Dept, National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Talant Sooronbaev
Niels H. Chavannes
1Dept of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Niels H. Chavannes
M. J. J. Rianne van der Kleij
1Dept of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. J. J. Rianne van der Kleij
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Figures

  • Tables
  • Supplementary Materials
  • FIGURE 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 1

    Tool used in each phase. Meta-QAT: Meta Quality Appraisal Tool; CASP: Critical Appraisal Skills Programme; CFIR: Consolidated Framework for Implementation Research; GRADE-CERQual: Grading of Recommendations Assessment, Development and Evaluation-Confidence in the Evidence from Reviews of Qualitative research.

  • FIGURE 2
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 2

    Flow diagram of screening process.

  • FIGURE 3
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 3

    Study settings and interventions. Symbols with two colours indicate the study covered both interventions. Half a symbol means half of the study was conducted in this setting and the other half in another setting.

  • FIGURE 4
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 4

    Full overview of implementation factors per domain, and the relative level of evidence for the factor.

  • FIGURE 5
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 5

    Free Respiratory Evaluation and Smoke-exposure reduction by primary Health cAre Integrated gRoups (FRESH AIR) Implementation Tool. #: These suggestions are based on the literature specific for interventions targeting chronic respiratory disease in low- and middle-income countries, and on additional, general implementation literature. See Appendix 7 for recommended use of the tool and details on the references.

Tables

  • Figures
  • Supplementary Materials
  • TABLE 1

    Characteristics of the included studies and critical appraisal, by author

    First author [ref.]Study designCountrySetting; populationInterventionSummary of appraisal
    RvRVA
    Aghi [49] #Qualitative study within an RCTIndiaPublic urban and rural schools; health educators, lead teachers and staffTobacco cessation+−−±
    Aldinger [65]¶Qualitative (institutional ethnography)ChinaPrimary to vocational schools; administrators, staff, teachers, students, and parentsTobacco prevention within programme of health-promoting schools± 1±±+
    Aldinger [66]¶Qualitative (institutional ethnography)ChinaPrimary to vocational schools; administrators, staff, teachers, students and parentsTobacco prevention within programme of health-promoting schools−+±+
    Asfar [64]Qualitative study within an RCTSyriaPrimary healthcare setting; physicians and medical studentsTobacco cessation+ 1−?±
    Assanangkornchai [82]Qualitative (action research)ThailandPrimary healthcare setting; healthcare workers (nurses, administrators, directors)Tobacco, alcohol and substance use screening and brief intervention± 1±±+
    Bheekie [60]Qualitative study preparing for an RCTSouth AfricaPrimary healthcare setting; trained nurses, with a supervisory position as care coordinatorsTrain-the-trainer programme on implementation of respiratory guidelines on (obstructive) lung diseases+++±
    Bteddini [63]Mixed-method, with quantitative survey and participatory approach for qualitative dataLebanonSeven public and seven private schools throughout the country; trained external facilitators training 10 sessions for 844 studentsWaterpipe smoking prevention/delay of starting to smoke± 1+++
    Castaldelli-Maia [51]QualitativeBrazilUrban psychosocial care units (primary care) across the country; diverse health professionals (e.g. dentist, nurses, physicians, managers)Tobacco cessation+ 1±?±
    Chatterjee [70]QualitativeIndiaRural villages; community members (programme managers, coordinators, health workers and stakeholders at village level)Tobacco-free village+ 1±±+
    Cruvinel [52]Quantitative, survey design (correlations)BrazilUrban, primary healthcare; 149 diverse workers (e.g. community health workers, nurses, physicians)Training on tobacco, alcohol and drug use screening and brief intervention±++±
    Elsey [78]Mixed-method, factors derived from qualitative data (action research)NepalUrban and rural primary healthcare; patients, healthcare providers, managers and policy makersTobacco cessation, behaviour support+ 1+++
    Goenka [71]+Mixed-method study within an RCTIndia32 Urban, public and private schools; professionals with a Master's degree in psychology, sociology or nutrition who taught teachers and peer leadersTobacco prevention by teachers and peer-leaders±+±±
    Groth-Marnat [85]QualitativeFijiTraditional village; community membersTobacco cessation+ 1±?±
    Ishaak [58]Mixed-method, factors derived from qualitative dataSurinameUrban junior high school; management and teachersTobacco and other drug prevention±±±±
    Khan [80]Mixed-method, embedded in RCT, factors derived from qualitative dataPakistan30 Primary and secondary level public healthcare facilities; care providers (15 received intervention, interviews in 4 of the centres)Integrated COPD/asthma care+ 1+++
    Malan [61]QualitativeSouth AfricaPrimary care practice; care providers (nurses and physicians)Brief behaviour change counselling (“5As”) for tobacco, diet, physical activity and alcohol abuse± 1+++
    Marsiglia [57]Qualitative for the factors reported, within a quantitative studyMexicoUrban public middle schools; teachersTobacco and other substance use prevention±−?−
    Mash [62]Qualitative, prospective (outcome mapping)South AfricaUrban and rural, primary care to specialised care with a focus on the public sector; doctors, clinical nurse practitioners, pharmacists, National Council for Medical Schemes, the Department of Health, universities and training bodies patientsAsthma-guideline implementation and dissemination+ 1±?±
    McAlister [81]Qualitative for the factors reported, within a quantitative studyRussiaCommunity level; hospital staff, intervention for community smokersStop smoking campaign+±?±
    Medeiros [53]Mixed-methods, factors derived from qualitative dataBrazilUrban schools; teachers, school administrators, coaches, other stakeholders (e.g. municipality) and studentsTobacco prevention within a drug use prevention programme±+++
    Mehanni [79]QualitativeNepalSmall rural hospital (managed through a public-private partnership)Quality improvement initiative for management of COPD+−?±
    Melson [77]Mixed-methods within pilot RCT; factors derived from qualitative data (quantitative data n.a., regard hypothetic factors prior to implementation). Pro- and retrospectiveMalaysiaSecondary school; studentsPeer-led anti-smoking intervention (smoke-free class)+ 1+++
    Nagler [72]#Qualitative, formative pilot study preparing for an RCTIndiaOne public urban and one rural school, not included in the RCT; health educators and teachersTobacco cessation – school based±++±
    Nichter [73]QualitativeIndia & IndonesiaLead public & private medical schools and outreach to their communitiesTraining network for tobacco prevention (curricula), outreach and clinic on smoking cessation+ 1−?±
    Ossip [56]Qualitative (Rapid Assessment Process)Dominican RepublicUrban, peri-urban & rural communities with active Community Technology Centers; a multidisciplinary team including specialists of psychology, anthropology, nursing, epidemiology, statistics and public health (from the US) and medicine (DR)Tobacco cessation – participatory approach+ 1±?±
    Pawar [50]#Qualitative factors reported within a quantitative study, embedded in an RCTIndia72 Public urban and rural schools; health educators, lead teachers and staffTobacco cessation - lay interventionist teaching teachers±−?−
    Pereira [54]Quantitative, population-based cross-sectional survey designBrazilUrban public and private schools; 263 school managers (headmasters, pedagogical coordinators, coordinators of the prevention programmes)Tobacco prevention within a drug use prevention programme± 1+±±
    Perry [74]+Qualitative study (translational research) within an RCT following translational researchIndia32 urban schools, half were public and half were private; school administration, teachers, and peer-leadersTobacco prevention± 1−?±
    Persai [75]QualitativeIndiaAt district level; senior district officialsTobacco control± 1+++
    Portes [55]Qualitative, retrospectiveBrazilUrban primary healthcare units in a medium-sized municipality; municipal programme coordinator, and senior health professionals trained on smoking cessation or local managersTobacco control – training healthcare professionals on facilitating treatment & prevention activities (Furthermore, interventions on governmental level, n.a. to our study)+ 1+++
    Prasodjo [76]Mixed-method, factors derived from qualitative data (amongst which participatory action research)IndonesiaRural community; local institutions (policy makers, medical staff, community leaders and other stakeholders)Post-partum smoke (‘Sei’) traditions – Behavioural change communication campaign targeting household air pollution+−±±
    Rosati [83]Mixed-methods, factors derived from qualitative dataThailandUrban family setting; health educators towards familiesTobacco, alcohol and other substance abuse prevention, sex education± 1±±±
    Sodhi [59]Mixed-methods, factors derived from qualitative dataMalawi30 urban and rural, government-funded and non-government funded health centres; primary healthcare workers: clinical officers, medical assistants, and nursesTrain-the-trainer on guideline use for providing integrated primary lung healthcare± 1±±+
    Vitavasiri [84]Quantitative questionnaireThailand676 Thai hospitals; personnelSmoke-free hospitals+ 1−?−
    Wang [67]QualitativeChinaCounty-level hospitals; health professionals, hospital president, director of preventive health, representatives of the hospitalsSmoke-free hospitals+ 1+++
    Xiao [68]Mixed-method, factors concerned qualitative dataChina41 Hospital across the country, the majority from a tobacco control network; medical doctors and directorsSmoke-free hospitals± 1−?+
    Ziedonis [69]QualitativeChinaHospital-based mental health centre; personnel and patientsSmoke-free hospitals+ 1−?±

    Studies were prospective unless otherwise indicated. Rv: relevance; R: reliability; V: validity; A: applicability to a wider public health context. RCT=randomised controlled trial. Scored in appraisal as: +: high; ±: medium; −

    : low; ?: unclear. Relevance '1': Evaluation of implementation was a primary outcome of the article. Articles with matching footnote indicators are from the same study. #: findings from Aghi et al. were excluded from the analysis, as Pawar et al. based their findings on the same study data and had higher appraisal scores. Nagler et al. based findings on a different study data (pilot study) and was included. +: findings from both studies were included as these were based on different study data.

    Supplementary Materials

    • Figures
    • Tables
    • Supplementary Material

      Please note: supplementary material is not edited by the Editorial Office, and is uploaded as it has been supplied by the author.

      Supplementary material ERJ-00127-2020.Supplement

    • Supplementary Material

      This one-page PDF can be shared freely online.

      Shareable PDF ERJ-00127-2020.Shareable

    PreviousNext
    Back to top
    View this article with LENS
    Vol 56 Issue 1 Table of Contents
    European Respiratory Journal: 56 (1)
    • Table of Contents
    • Index by author
    Email

    Thank you for your interest in spreading the word on European Respiratory Society .

    NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

    Enter multiple addresses on separate lines or separate them with commas.
    Implementing lung health interventions in low- and middle-income countries: a FRESH AIR systematic review and meta-synthesis
    (Your Name) has sent you a message from European Respiratory Society
    (Your Name) thought you would like to see the European Respiratory Society web site.
    CAPTCHA
    This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
    Print
    Alerts
    Sign In to Email Alerts with your Email Address
    Citation Tools
    Implementing lung health interventions in low- and middle-income countries: a FRESH AIR systematic review and meta-synthesis
    Evelyn A. Brakema, Debbie Vermond, Hilary Pinnock, Christos Lionis, Bruce Kirenga, Pham Le An, Talant Sooronbaev, Niels H. Chavannes, M. J. J. Rianne van der Kleij
    European Respiratory Journal Jul 2020, 56 (1) 2000127; DOI: 10.1183/13993003.00127-2020

    Citation Manager Formats

    • BibTeX
    • Bookends
    • EasyBib
    • EndNote (tagged)
    • EndNote 8 (xml)
    • Medlars
    • Mendeley
    • Papers
    • RefWorks Tagged
    • Ref Manager
    • RIS
    • Zotero

    Share
    Implementing lung health interventions in low- and middle-income countries: a FRESH AIR systematic review and meta-synthesis
    Evelyn A. Brakema, Debbie Vermond, Hilary Pinnock, Christos Lionis, Bruce Kirenga, Pham Le An, Talant Sooronbaev, Niels H. Chavannes, M. J. J. Rianne van der Kleij
    European Respiratory Journal Jul 2020, 56 (1) 2000127; DOI: 10.1183/13993003.00127-2020
    del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
    Full Text (PDF)

    Jump To

    • Article
      • Abstract
      • Abstract
      • Introduction
      • Methods
      • Results
      • Discussion
      • Supplementary material
      • Shareable PDF
      • Acknowledgements
      • Footnotes
      • References
    • Figures & Data
    • Info & Metrics
    • PDF
    • Tweet Widget
    • Facebook Like
    • Google Plus One

    More in this TOC Section

    • The pathophysiological role of novel pulmonary arterial hypertension gene SOX17
    • Understanding the key issues in the treatment of uncontrolled persistent asthma with type 2 inflammation
    • When things go wrong: Exploring possible mechanisms driving the progressive fibrosis phenotype in interstitial lung diseases
    Show more Review

    Related Articles

    Navigate

    • Home
    • Current issue
    • Archive

    About the ERJ

    • Journal information
    • Editorial board
    • Reviewers
    • CME
    • Press
    • Permissions and reprints
    • Advertising

    The European Respiratory Society

    • Society home
    • myERS
    • Privacy policy
    • Accessibility

    ERS publications

    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS books online
    • ERS Bookshop

    Help

    • Feedback

    For authors

    • Instructions for authors
    • Submit a manuscript
    • ERS author centre

    For readers

    • Alerts
    • Subjects
    • Podcasts
    • RSS

    Subscriptions

    • Accessing the ERS publications

    Contact us

    European Respiratory Society
    442 Glossop Road
    Sheffield S10 2PX
    United Kingdom
    Tel: +44 114 2672860
    Email: journals@ersnet.org

    ISSN

    Print ISSN:  0903-1936
    Online ISSN: 1399-3003

    Copyright © 2021 by the European Respiratory Society