Extract
Pulmonary endarterectomy (PEA) is the treatment of choice of chronic thromboembolic pulmonary hypertension (CTEPH) [1]. However, successfully operated patients may continue to suffer from dyspnoea and limitation of exercise capacity, despite improvement or even normalisation of pulmonary artery pressure (PAP), cardiac output (CO) and pulmonary vascular resistance (PVR) [2]. This absence of complete symptomatic recovery has been explained by a decreased right ventricular (RV) function reserve due to persistent increased afterload [3, 4], related to decreased pulmonary arterial compliance (PCa) more than to mildly increased PVR [5, 6]. There is therefore interest in assessing PCa in patients during the follow-up of PEA.
Abstract
In CTEPH patients who have undergone pulmonary endarterectomy, exercise capacity is better associated with changes in invasively measured pulmonary arterial compliance than with changes in magnetic resonance imaging of pulmonary artery stiffness http://bit.ly/30DAWUj
Footnotes
Author contributions: S. Ghio made substantial contributions to conception and to the design of the study and to interpretation of data; drafted the submitted article; and provided final approval of the version to be published. S. Ghio takes responsibility for (is the guarantor of) the content of the manuscript, including the data and analysis. G. Crimi, S. Guida, A. Valentini, A. Celentano, M. Pin, C. Raineri, A. Turco, L. Oltrona Visconti, R. Naeije and A.M. D'Armini have made substantial contributions to conception of the study, to interpretation of data; have revised the manuscript critically for important intellectual content and has provided final approval of the version to be published; G. Crimi has also analysed the data.
Conflict of interest: S. Ghio has nothing to disclose.
Conflict of interest: G. Crimi has nothing to disclose.
Conflict of interest: S. Guida has nothing to disclose.
Conflict of interest: A. Valentini has nothing to disclose.
Conflict of interest: A. Celentano has nothing to disclose.
Conflict of interest: M. Pin has nothing to disclose.
Conflict of interest: C. Raineri has nothing to disclose.
Conflict of interest: A. Turco has nothing to disclose.
Conflict of interest: L. Scelsi has nothing to disclose.
Conflict of interest: L. Oltrona Visconti has nothing to disclose.
Conflict of interest: R. Naeije has nothing to disclose.
Conflict of interest: A.M. D'Armini has nothing to disclose.
- Received November 8, 2019.
- Accepted January 12, 2020.
- Copyright ©ERS 2020
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