Table of Contents

Original Articles

• Cystic fibrosis

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    Structural determinants of long-term functional outcomes in young children with cystic fibrosis

    Lidija Turkovic, Daan Caudri, Tim Rosenow, Oded Breuer, Conor Murray, Harm A.W.M. Tiddens, Fiona Ramanauskas, Sarath C. Ranganathan, Graham L. Hall, Stephen M. Stick on behalf of AREST CF

    European Respiratory Journal 55 (5) 1900748; DOI: 10.1183/13993003.00748-2019 Published 21 May 2020

• Pulmonary hypertension

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    Physiological predictors of survival in patients with sarcoidosis-associated pulmonary hypertension: results from an international registry

    Oksana A. Shlobin, Vasilis Kouranos, Scott D. Barnett, Esam H. Alhamad, Daniel A. Culver, Joseph Barney, Francis C. Cordova, Eva M. Carmona, Mary Beth Scholand, Marlies Wijsenbeek, Sivagini Ganesh, Elyse E. Lower, Peter J. Engel, John Wort, Laura Price, Athol U. Wells, Steven D. Nathan, Robert P. Baughman

    European Respiratory Journal 55 (5) 1901747; DOI: 10.1183/13993003.01747-2019 Published 14 May 2020

• Pulmonary hypertension and genetics

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    Phenotype and outcome of pulmonary arterial hypertension patients carrying a TBX4 mutation

    Pierre Thoré, Barbara Girerd, Xavier Jaïs, Laurent Savale, Maria-Rosa Ghigna, Mélanie Eyries, Marilyne Levy, Caroline Ovaert, Amélie Servettaz, Anne Guillaumot, Claire Dauphin, Céline Chabanne, Emmanuel Boiffard, Vincent Cottin, Frédéric Perros, Gérald Simonneau, Olivier Sitbon, Florent Soubrier, Damien Bonnet, Martine Remy-Jardin, Ari Chaouat, Marc Humbert, David Montani

    European Respiratory Journal 55 (5) 1902340; DOI: 10.1183/13993003.02340-2019 Published 14 May 2020

• Pleural disease

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    The Pleural Effusion And Symptom Evaluation (PLEASE) study of breathlessness in patients with a symptomatic pleural effusion

    Sanjeevan Muruganandan, Maree Azzopardi, Rajesh Thomas, Deirdre B. Fitzgerald, Yi Jin Kuok, Hui Min Cheah, Catherine A. Read, Charley A. Budgeon, Peter R. Eastwood, Susan Jenkins, Bhajan Singh, Kevin Murray, Y.C. Gary Lee

    European Respiratory Journal 55 (5) 1900980; DOI: 10.1183/13993003.00980-2019 Published 14 May 2020

• Asthma

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    Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis

    Kay Wang, Jan Y. Verbakel, Jason Oke, Alexander Fleming-Nouri, Josh Brewin, Nia Roberts, Norihiro Harada, Ryo Atsuta, Kazuhisa Takahashi, Kazutaka Mori, Tomoyuki Fujisawa, Toshihiro Shirai, Tomotaka Kawayama, Hiromasa Inoue, Stephen Lazarus, Stanley Szefler, Fernando Martinez, Dominick Shaw, Ian D. Pavord, Mike Thomas

    European Respiratory Journal 55 (5) 1902150; DOI: 10.1183/13993003.02150-2019 Published 21 May 2020
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    Mepolizumab effectiveness and identification of super-responders in severe asthma

    Erin S. Harvey, David Langton, Constance Katelaris, Sean Stevens, Claude S. Farah, Andrew Gillman, John Harrington, Mark Hew, Vicky Kritikos, Naghmeh Radhakrishna, Philip Bardin, Matthew Peters, Paul N. Reynolds, John W. Upham, Melissa Baraket, Simon Bowler, Jeffrey Bowden, Jimmy Chien, Li Ping Chung, Christopher Grainge, Christine Jenkins, Gregory P. Katsoulotos, Joy Lee, Vanessa M. McDonald, Helen K. Reddel, Janet Rimmer, Peter A.B. Wark, Peter G. Gibson

    European Respiratory Journal 55 (5) 1902420; DOI: 10.1183/13993003.02420-2019 Published 21 May 2020
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    Aberrant anti-viral response of natural killer cells in severe asthma

    Justine Devulder, Cécile Chenivesse, Valérie Ledroit, Stéphanie Fry, Pierre-Emmanuel Lobert, Didier Hober, Anne Tsicopoulos, Catherine Duez

    European Respiratory Journal 55 (5) 1802422; DOI: 10.1183/13993003.02422-2018 Published 14 May 2020
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    Adherence to inhaled corticosteroids and clinical outcomes in mepolizumab therapy for severe asthma

    Gráinne d'Ancona, Joanne Kavanagh, Cris Roxas, Linda Green, Mariana Fernandes, Louise Thomson, Jaideep Dhariwal, Alexandra M. Nanzer, David J. Jackson, Brian D. Kent

    European Respiratory Journal 55 (5) 1902259; DOI: 10.1183/13993003.02259-2019 Published 7 May 2020

• Asthma and paediatrics

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    Does treatment guided by exhaled nitric oxide fraction improve outcomes in subgroups of children with asthma?

    Shona S. Fielding, Marielle Pijnenburg, Johan de Jongste, Katherine Pike, Graham Roberts, Helen Petsky, Anne B. Chang, Maria Fritsch, Thomas Frischer, Stanley J. Szefler, Peter Gergen, Francoise Vermeulen, Robin Vael, Steve S. Turner

    European Respiratory Journal 55 (5) 1901879; DOI: 10.1183/13993003.01879-2019 Published 21 May 2020

• Paediatrics

  • Open Access

    Dissimilarity of the gut–lung axis and dysbiosis of the lower airways in ventilated preterm infants

    David Gallacher, Emma Mitchell, Dagmar Alber, Richard Wach, Nigel Klein, Julian R. Marchesi, Sailesh Kotecha

    European Respiratory Journal 55 (5) 1901909; DOI: 10.1183/13993003.01909-2019 Published 7 May 2020

• Infectious disease

  • Open Access

    Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis

    Wei-jie Guan, Wen-hua Liang, Yi Zhao, Heng-rui Liang, Zi-sheng Chen, Yi-min Li, Xiao-qing Liu, Ru-chong Chen, Chun-li Tang, Tao Wang, Chun-quan Ou, Li Li, Ping-yan Chen, Ling Sang, Wei Wang, Jian-fu Li, Cai-chen Li, Li-min Ou, Bo Cheng, Shan Xiong, Zheng-yi Ni, Jie Xiang, Yu Hu, Lei Liu, Hong Shan, Chun-liang Lei, Yi-xiang Peng, Li Wei, Yong Liu, Ya-hua Hu, Peng Peng, Jian-ming Wang, Ji-yang Liu, Zhong Chen, Gang Li, Zhi-jian Zheng, Shao-qin Qiu, Jie Luo, Chang-jiang Ye, Shao-yong Zhu, Lin-ling Cheng, Feng Ye, Shi-yue Li, Jin-ping Zheng, Nuo-fu Zhang, Nan-shan Zhong, Jian-xing He on behalf of the China Medical Treatment Expert Group for COVID-19

    European Respiratory Journal 55 (5) 2000547; DOI: 10.1183/13993003.00547-2020 Published 14 May 2020
  • Open Access

    Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study

    Rong-Hui Du, Li-Rong Liang, Cheng-Qing Yang, Wen Wang, Tan-Ze Cao, Ming Li, Guang-Yun Guo, Juan Du, Chun-Lan Zheng, Qi Zhu, Ming Hu, Xu-Yan Li, Peng Peng, Huan-Zhong Shi

    European Respiratory Journal 55 (5) 2000524; DOI: 10.1183/13993003.00524-2020 Published 7 May 2020

• COPD

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    The effect of exacerbation history on outcomes in the IMPACT trial

    David M.G. Halpin, Mark T. Dransfield, MeiLan K. Han, C. Elaine Jones, Sally Kilbride, Peter Lange, David A. Lipson, David A. Lomas, Fernando J. Martinez, Steve Pascoe, Dave Singh, Robert Wise, Gerard J. Criner

    European Respiratory Journal 55 (5) 1901921; DOI: 10.1183/13993003.01921-2019 Published 21 May 2020
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    Earlier palliative home care is associated with patient-centred medical resource utilisation and lower costs in the last 30 days before death in COPD: a population-level decedent cohort study

    Charlotte Scheerens, Kristof Faes, Peter Pype, Kim Beernaert, Guy Joos, Eric Derom, Joachim Cohen, Luc Deliens, Kenneth Chambaere

    European Respiratory Journal 55 (5) 1901139; DOI: 10.1183/13993003.01139-2019 Published 21 May 2020
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    Blood eosinophil count in the general population: typical values and potential confounders

    Sylvia Hartl, Marie-Kathrin Breyer, Otto C. Burghuber, Alina Ofenheimer, Andrea Schrott, Matthias H. Urban, Alvar Agusti, Michael Studnicka, Emiel F.M. Wouters, Robab Breyer-Kohansal

    European Respiratory Journal 55 (5) 1901874; DOI: 10.1183/13993003.01874-2019 Published 14 May 2020

• COPD and basic science

  • Open Access

    Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue

    Prajakta Jogdand, Premkumar Siddhuraj, Michiko Mori, Caroline Sanden, Jimmie Jönsson, Andrew F. Walls, Jennifer Kearley, Alison A. Humbles, Roland Kolbeck, Leif Bjermer, Paul Newbold, Jonas S. Erjefält

    European Respiratory Journal 55 (5) 1900110; DOI: 10.1183/13993003.00110-2019 Published 7 May 2020