Abstract
Predicted versus observed postoperative lung function six months after lung resection: A comparation between patients with and without COPD
Introduction: Lung resection is the curative treatment for non-small cell lung cancer. Predicted for postoperative of FEV1, DLCO and VO2 are used to risk assessment.
Objectives: To compare predicted postoperative (ppo) values of FEV1, DLCO and VO2peak with observed values six months after lung resection for lung cancer in patients with and without COPD.
Methods: Prospective cohort study. 10 patients in CPOD group and 8 in Control group were evaluated in preoperative period (spirometry, DLCO, CPET). Ppo VEF1, ppo DLCO and ppo VO2peak values were obtained according Nakahara et al. Six month later the patients were clinically and functionally reevaluated (spirometry, DLCO, CPET). Student’s t-test for independent samples and Mann-Whitney test for independent samples. For dependent samples, the t-test and Wilcoxon test.
Results: In both groups, the majority of the patients were male. In the COPD group, there were more current smokers and in the Control group more former smokers. Follow-up after six months showed no difference in FEV1 or DLCO values intra-group. Control group had a decrease in V̇O2peak six month later (20.8±7.1mL/kg/min to 16.3±5.3mL/kg/min;p=0,007). This difference was not observed in the COPD group (15.6±3.7mL/kg/min to 14.5±4.1mL/kg/min;p=0,07). In the COPD group, ppoFEV1 and ppoV̇O2peak were lower than observed six month later (54.9±10.7% versus 62.1±14.5%;p=0,04; 12.8±3.6mL/kg/min versus 14.5±4.1mL/kg/min;p=0,007).
Conclusion: The COPD group had an overestimation of post-operative functional loss.
Footnotes
Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA794.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2019