Abstract
Introduction: Childhood interstitial lung diseases (chILD) are heterogeneous group of lung diseases which are very rare in childhood. In this study, we aimed to evaluate patients who were referred to a tertiary pediatric pulmonology department with the suspicion of chILD.
Methods: The data of children with chILD in the pediatric pulmonology department between 2007-2018 were evaluated retrospectively. Patients’ age, gender, complaints and diagnosis were noted. Patients’ diagnosis were categorized into Diffuse Parenchymal Lung Disease categories and subcategories.
Results: Between 2007-2018, 5965 patients were evaluated in the pediatric pulmonology department; 354 (5.9 %) of them were referred with the suspicion of chILD. The mean age of the patients was 7.3 ± 6.1 years. The most common complaints were respiratory distress, shortness of breath and coughing. Two hundred and thirty-one (65.2 %) of the patients were diagnosed with ILD. The most common diagnosis of chILD were bronchopulmonary dysplasia, bronchiolitis obliterans, pulmonary hypertension and pulmonary hypoplasia. The chILD related with systemic diseases were most commonly detected with malignancy. The most rare chILD subcategories were included surfactant dysfunction disorders (ABCA3, SFTPC mutations) and Neuroendocrine cell hyperplasia of infancy (NEHI).
Conclusions: Patients with chILD are evaluated in a wide spectrum according to age of diagnosis, symptoms, underlying diseases or radiological findings. It is important for clinicians to keep in mind chILD in terms of early diagnosis and possible treatments in children with dyspnea, pulmonary infiltration, hypoxia or restrictive disorder in pulmonary function tests.
Footnotes
Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA5188.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2019