Abstract
Introduction: Chronic obstructive pulmonary disease (COPD) is currently one of the leading causes of death worldwide. COPD frequently occur together with Cardiovascular disease. The coexistence of the two diseases are associated with worse outcomes than either condition alone. ABPM and 24h arterial stiffness parameters profile measurement in stabile COPD patients and control individuals for the detection of increased cardiovascular risk and for the detection of early atherosclerosis in COPD.
Methods: We measured 23 healthy (54 ± 9,1 years) and 26 COPD (57 ± 9 years) subjectsin the study. ABPM and 24h arterial stiffness parameters were oscillometrically measured with Arteriograph 24.
Results: We have found significant higher day- and night averages in systolic blood pressure (SBPbr) {p=0,032, p<0,001} systolic aortic blood pressure (SBPao) {p<0,001, p<0,001} aortic pulse wave velocity (PWVao) {p<0,001, p<0,001} and aortic augmentation index (Aixao) {p<0,001, p<0,001} in COPD patients than controls. In 26% of COPD patients did not reduced the nighttime blood pressure compared to daytime systolic blood pressure.
Conclusion: In this study we found elevated day- and night blood pressure and arterial stiffness parameters in COPD patients. These results are indicating the presence of earlier atherosclerosis and higher cardiovascular risk in patients with COPD than in control individuals.
Footnotes
Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA5016.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2019