Abstract
Introduction: Knowledge of patient priorities is important to select appropriate treatment. Discrete choice experiment (DCE) methodology involves making trade-offs which indicate patients’ preferences.
Aim: To determine the relative importance to participants in the PRACTICAL study, a 12-month open-label RCT of symptom-driven budesonide-formoterol versus regular budesonide plus as-needed terbutaline, of attributes distinguishing these regimens.
Methods: Regimen attributes were identified using focus groups. Participants finishing the PRACTICAL study after 26 March 2018 at 6/14 sites completed one of two DCEs based on their stated preference for as-needed combined preventer/reliever therapy or regular preventer and as needed reliever. 1000minds software and the PAPRIKA method were used for the DCEs.
Results: The DCEs were completed by 296 of 407 (73%) eligible participants. Figure 1 shows preference weights representing the relative importance of the attributes in the DCEs. Frequency of breathlessness had a stronger influence on choice than risk of flare up, type of regimen or steroid dose. Within each DCE, attribute weights were not affected by the patient’s randomisation group.
Conclusions: In these DCEs, participant’s preferences were influenced by several attributes in addition to as-needed versus regular treatment. The relative importance of such attributes should be considered during shared decision-making with patients.
Footnotes
Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4189.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2019
