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Can Neutrophil/lymphocyte Ratio, C-reactive protein (CRP) and Procalcitonin predict the hospitalization time in patients with lower tract respiratory infections ?

Ali Çetinkaya, Mehmet Atilla Uysal, Elif Yelda Niksarlıoglu, Ayşe Sinem Durna, Nagihan Orhan Ozer, Gungor Camsarı
European Respiratory Journal 2019 54: PA3849; DOI: 10.1183/13993003.congress-2019.PA3849
Ali Çetinkaya
1Clinic of Chest Diseases, Istanbul Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, İstanbul, Turkey
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  • For correspondence: dralicetinkaya02@gmail.com
Mehmet Atilla Uysal
1Clinic of Chest Diseases, Istanbul Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, İstanbul, Turkey
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Elif Yelda Niksarlıoglu
1Clinic of Chest Diseases, Istanbul Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, İstanbul, Turkey
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Ayşe Sinem Durna
1Clinic of Chest Diseases, Istanbul Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, İstanbul, Turkey
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Nagihan Orhan Ozer
1Clinic of Chest Diseases, Istanbul Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, İstanbul, Turkey
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Gungor Camsarı
1Clinic of Chest Diseases, Istanbul Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, İstanbul, Turkey
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Abstract

Aim: At hospital admission some inflammatory markers like C-Reactive Protein (CRP), Procalcitonin (PCT) and Neutrophil/ Lymphocyte Ratio (NLR) were studied on patient mortality and hospitalization time in Intensive Care Unit (ICU) and COPD exacerbations. In this study, we investigated the predictor role of CRP, PCT and NLR on the hospitalization time in patients with Lower Respiratory Tract Infections (LRTI) in a chest diseases clinic.

Methods: In this observational, cross-sectional and retrospective study, we evaluated the patients who were hospitalized in our chest disease clinic between 2016 and 2018. We included 1153 patients who were diagnosed with pneumonia, COPD exacerbation, exacerbation of bronchiectasis, acute bronchitis, parapneumonic effusion, and empyema according to ICD-10 criteria.

Results: Median hospitalization time was 7 (Interquartile Range, IQR:5-11). Median NLR was 6.45 (IQR:3.78-11.71), median CRP number was 88 mg/L (IQR:27.9-185.6 mg/L), and median PCT number was 0.26 ng/ml (IQR:0.09-0.61ng/ml). 587 patients have NLR≥6.45 and median hospitalization time was 8( IQR:6-11) days. 566 patients have NLR<6.45 and hospitalization time was 7 (IQR:5-10) days. There was a significant difference between two groups (p<0.001). 580 patients have CRP>=88mg/L and median hospitalization time was 8(IQR:6-12) days. 573 patients have CRP<88 mg/L and hospitalization time was 6(IQR:4-9) days. There was a significant difference between the two groups (p<0.001).

Conclusion: We found that CRP and NLR were significant to predict hospitalization time in the patients with LRTI in the chest clinic.

  • COPD - exacerbations
  • Pneumonia
  • Biomarkers

Footnotes

Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA3849.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2019
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Can Neutrophil/lymphocyte Ratio, C-reactive protein (CRP) and Procalcitonin predict the hospitalization time in patients with lower tract respiratory infections ?
Ali Çetinkaya, Mehmet Atilla Uysal, Elif Yelda Niksarlıoglu, Ayşe Sinem Durna, Nagihan Orhan Ozer, Gungor Camsarı
European Respiratory Journal Sep 2019, 54 (suppl 63) PA3849; DOI: 10.1183/13993003.congress-2019.PA3849

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Can Neutrophil/lymphocyte Ratio, C-reactive protein (CRP) and Procalcitonin predict the hospitalization time in patients with lower tract respiratory infections ?
Ali Çetinkaya, Mehmet Atilla Uysal, Elif Yelda Niksarlıoglu, Ayşe Sinem Durna, Nagihan Orhan Ozer, Gungor Camsarı
European Respiratory Journal Sep 2019, 54 (suppl 63) PA3849; DOI: 10.1183/13993003.congress-2019.PA3849
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